Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR004659

Source: InterPro

Description

IPR004659 is a Ribonuclease E/G.

<p>Ribonuclease E and ribonuclease G are related enzymes that cleave a wide variety of RNAs [[cite:PUB00033641], [cite:PUB00097829]]. In Escherichia coli, both enzymes have been shown to play a role in the maturation of the 5' end of 16S RNA [[cite:PUB00056899]]. RNase E is a major subunit the eubacterial degradosome - a large, multiprotein, multienzyme complex involved in RNA processing and degradation in E. coli and other proteobacteria [[cite:PUB00033948]]. These enzymes prefer 5'-monophosphorylated 5'-triphosphorylated substrates. The 5'-monophosphate-assisted cleavage requires at least 2 and preferably 3 or more unpaired 5'-terminal nucleotides [[cite:PUB00097830]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of
GO:0004540
Molecular function Ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
Subterm of
GO:0006396
Biological process RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
Subterm of
Part of

Associated Lotus transcripts 5

Transcript Name Description Predicted domains Domain count
Lj2g3v2220800.1
– Ribonuclease E [Medicago truncatula] gi|357490525|ref|XP_003615550.1|
Domains
7
LotjaGi1g1v0125400.1
– Ribonuclease E/G family protein; TAIR: AT2G04270.1 RNAse E/G-like protein; Swiss-Prot: sp|F4IV66|RNE_ARATH Ribonuclease E/G-like protein, chloroplastic; TrEMBL-Plants: tr|I1MB77|I1MB77_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0125400
Domains
14
LotjaGi1g1v0125400.2
– Ribonuclease E/G family protein; TAIR: AT2G04270.1 RNAse E/G-like protein; Swiss-Prot: sp|F4IV66|RNE_ARATH Ribonuclease E/G-like protein, chloroplastic; TrEMBL-Plants: tr|A0A0B2S438|A0A0B2S438_GLYSO Ribonuclease E; Found in the gene: LotjaGi1g1v0125400
Domains
14
LotjaGi1g1v0125400.3
– Ribonuclease E/G family protein; TAIR: AT2G04270.2 RNAse E/G-like protein; Swiss-Prot: sp|F4IV66|RNE_ARATH Ribonuclease E/G-like protein, chloroplastic; TrEMBL-Plants: tr|K7M7Z2|K7M7Z2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0125400
Domains
6
LotjaGi1g1v0125400.4
– Ribonuclease E/G family protein; TAIR: AT2G04270.2 RNAse E/G-like protein; Swiss-Prot: sp|F4IV66|RNE_ARATH Ribonuclease E/G-like protein, chloroplastic; TrEMBL-Plants: tr|K7M7Z2|K7M7Z2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0125400
Domains
6

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00757 TIGRFAM 1 20.00