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IPR005787

Source: InterPro

Description

IPR005787 is a Threonine dehydratase, biosynthetic.

<p>Threonine dehydratase ([ec:4.3.1.19]) (TDH) catalyzes the dehydratation of threonine into alpha-ketobutarate and ammonia. In Escherichia coli and other microorganisms, two classes of TDH are known to exist. One is involved in the biosynthesis of isoleucine, the other in hydroxamino acid catabolism.</p> <p>This entry describes a form of threonine dehydratase with two copies of the threonine dehydratase C-terminal domain ([interpro:IPR001721]_. Members with known function participate in isoleucine biosynthesis and are inhibited by isoleucine.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004794
Molecular function L-threonine ammonia-lyase activity Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3.
Subterm of
GO:0009097
Biological process Isoleucine biosynthetic process The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
Subterm of

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj1g3v4450420.1
– PREDICTED: threonine dehydratase biosynthetic, chloroplastic-like [Glycine max] gi|356548297|ref|XP_003542539.1|
Domains
22
LotjaGi1g1v0714200.1
– Threonine dehydratase; TAIR: AT3G10050.1 L-O-methylthreonine resistant 1; Swiss-Prot: sp|Q9ZSS6|THD1_ARATH Threonine dehydratase biosynthetic, chloroplastic; TrEMBL-Plants: tr|A0A0L9TWQ1|A0A0L9TWQ1_PHAAN Threonine dehydratase; Found in the gene: LotjaGi1g1v0714200
Domains
23
LotjaGi5g1v0089100.1
– Threonine dehydratase; TAIR: AT3G10050.1 L-O-methylthreonine resistant 1; Swiss-Prot: sp|Q9ZSS6|THD1_ARATH Threonine dehydratase biosynthetic, chloroplastic; TrEMBL-Plants: tr|A0A0L9TWQ1|A0A0L9TWQ1_PHAAN Threonine dehydratase; Found in the gene: LotjaGi5g1v0089100
Domains
20
LotjaGi5g1v0089100.2
– Threonine dehydratase; TAIR: AT3G10050.1 L-O-methylthreonine resistant 1; Swiss-Prot: sp|Q9ZSS6|THD1_ARATH Threonine dehydratase biosynthetic, chloroplastic; TrEMBL-Plants: tr|A0A0L9TWQ1|A0A0L9TWQ1_PHAAN Threonine dehydratase; Found in the gene: LotjaGi5g1v0089100
Domains
19

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd04907 CDD 1 25.00