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IPR005999

Source: InterPro

Description

IPR005999 is a Glycerol kinase.

<p>Glycerol kinase ([ec:2.7.1.30]) is a bacterial sugar kinase which catalyses the Mg-ATP-dependent phosphorylation of glycerol to yield glycerol 3-phosphate. The enzyme from Escherichia coli is an allosteric regulatory enzyme whose activity is inhibited by fructose 1,6-bisphosphate (FBP) and the glucose-specific phosphocarrier of the phosphoenolpyruvate:glycose phosphotransferase system, IIA(Glc), structural studies suggest a nucleophilic in-line transfer mechanism for the ATP-dependent phosphorylation of glycerol by glycerol kinase [[cite:PUB00007924]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004370
Molecular function Glycerol kinase activity Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+).
Subterm of
GO:0006072
Biological process Glycerol-3-phosphate metabolic process The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj3g3v2174780.1
– Glycerol kinase [Medicago truncatula] gi|357468137|ref|XP_003604353.1|
Domains
15
LotjaGi3g1v0354200.1
– Glycerol kinase-like protein; TAIR: AT1G80460.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9M8L4|GLPK_ARATH Glycerol kinase; TrEMBL-Plants: tr|G7JGV7|G7JGV7_MEDTR Glycerol kinase-like protein; Found in the gene: LotjaGi3g1v0354200
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR01311 TIGRFAM 1 50.00