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IPR018483

Description

IPR018483 is a Carbohydrate kinase, FGGY, conserved site.

<p>FGGY carbohydrate kinases carry out ATP-dependent phosphorylation on one out of at least nine distinct sugar substrates [[cite:PUB00080793]]. These enzymes include L-ribulokinase ([ec:2.7.1.16]) (gene araB); Erythriol kinase ([ec:2.7.1.27]) (gene eryA); L-fucolokinase ([ec:2.7.1.51]) (gene fucK); gluconokinase ([ec:2.7.1.12]) (gene gntK); glycerol kinase ([ec:2.7.1.30]) (gene glpK); xylulokinase ([ec:2.7.1.17]) (gene xylB); L-xylulose kinase ([ec:2.7.1.53]) (gene lyxK), D-ribulokinase ([ec:2.7.1.47]) (gene rbtK); and rhamnulokinase ([ec:2.7.1.5]) (gene rhaB). This family also contains a divergent subfamily functioning in quorum sensing, which phosphorylates AI-2, a bacterial signaling molecule derived from 4,5-dihydroxy-2,3-pentanedione (DPD) [[cite:PUB00056209]].</p> <p>This entry represents conserved regions found in the central and C-terminal regions of these enzymes.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
Molecular function Phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Glycerol kinase [Medicago truncatula] gi|357468137|ref|XP_003604353.1| 15
10
Glycerol kinase-like protein; TAIR: AT1G80460.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9M8L4|GLPK_ARATH Glycerol kinase; TrEMBL-Plants: tr|G7JGV7|G7JGV7_MEDTR Glycerol kinase-like protein; Found in the gene: LotjaGi3g1v0354200 16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR01311 TIGRFAM 1 33.33