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IPR006005 is a Glutamate synthase, NADH/NADPH, small subunit 1.
<p>This family includes glutamate synthases from all cellular organisms. This enzyme, involved in the assimilation of ammonia and glutamate biosynthesis, transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate.</p> <p><reaction> 2 L-glutamate + NADP<sup>+</sup> = L-glutamine + 2-oxoglutarate + NADPH + H<sup>+</sup></reaction></p> <p>Several archaeal and deeply branched bacterial lineages of a homotetrameric show several forms of the small subunit of this enzyme: the NADPH-dependent or NADH-dependent glutamate synthase ([ec:1.4.1.13] and [ec:1.4.1.14] respectively).</p> <p>Members from fungi and plants are also included in this entry.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Glutamate biosynthetic process | The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. | ||
| Molecular function | Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: LOW QUALITY PROTEIN: glutamate synthase [NADH] gi|502124343|ref|XP_004498486.1| | 17 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A0B2SWZ8|A0A0B2SWZ8_GLYSO Glutamate synthase [NADH], amyloplastic; Found in the gene: LotjaGi1g1v0224700 | 40 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A072VE66|A0A072VE66_MEDTR NADH glutamate synthase; Found in the gene: LotjaGi1g1v0224700 | 36 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A0B2SWZ8|A0A0B2SWZ8_GLYSO Glutamate synthase [NADH], amyloplastic; Found in the gene: LotjaGi1g1v0224700 | 40 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A072VE66|A0A072VE66_MEDTR NADH glutamate synthase; Found in the gene: LotjaGi1g1v0224700 | 45 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A0B2SWZ8|A0A0B2SWZ8_GLYSO Glutamate synthase [NADH], amyloplastic; Found in the gene: LotjaGi1g1v0224700 | 37 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A0B2SWZ8|A0A0B2SWZ8_GLYSO Glutamate synthase [NADH], amyloplastic; Found in the gene: LotjaGi1g1v0224700 | 40 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A0S3RN10|A0A0S3RN10_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0224700 | 40 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|Q93WZ7|Q93WZ7_PHAVU NADH glutamate synthase; Found in the gene: LotjaGi1g1v0224700 | 28 | ||
| – | Glutamate synthase, putative; TAIR: AT5G53460.1 NADH-dependent glutamate synthase 1; Swiss-Prot: sp|Q03460|GLSN_MEDSA Glutamate synthase [NADH], amyloplastic; TrEMBL-Plants: tr|A0A072VE66|A0A072VE66_MEDTR NADH glutamate synthase; Found in the gene: LotjaGi1g1v0224700 | 45 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 10.00 |