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IPR006093 is a Oxygen oxidoreductase covalent FAD-binding site.
<p>This entry represents the conserved region around the histidine that binds the FAD group, which is conserved in these enzymes.</p> <p>Some oxygen-dependent oxidoreductases are flavoproteins that contain a covalently bound FAD group which is attached to a histidine via an 8-alpha- (N3-histidyl)-riboflavin linkage. These proteins include:</p> <ul> <li>(R)-6-hydroxynicotine oxidase (EC 1.5.3.6) (6-HDNO) [[cite:PUB00001355]], a bacterial enzyme that catalyzes the oxygen-dependent degradation of 6-hydroxynicotine into 6-hydroxypyrid-N-methylosmine.</li> <li>Plant reticuline oxidase (EC 1.21.3.3) [[cite:PUB00004761]] (berberine-bridge-forming enzyme), an enzyme that catalyzes the oxidation of (S)-reticuline into (S)- scoulerine in the pathway leading to benzophenanthridine alkaloids.</li> <li>L-gulonolactone oxidase (EC 1.1.3.8) (l-gulono-gamma-lactone oxidase) [[cite:PUB00002469]], a mammalian enzyme which catalyzes the oxidation of L-gulono-1,4-lactone to L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.</li> <li>D-arabinono-1,4-lactone oxidase (EC 1.1.3.24) (L-galactonolactone oxidase), a yeast enzyme involved in the biosynthesis of D-erythroascorbic acid [[cite:PUB00010580]].</li> <li>Mitomycin radical oxidase [[cite:PUB00002249]], a bacterial protein involved in mitomycin resistance and that probably oxidizes the reduced form of mitomycins.</li> <li>Cytokinin oxidase (EC 1.4.3.18), a plant enzyme.</li> <li>Rhodococcus fascians fasciation locus protein fas5.</li> </ul>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: cytokinin dehydrogenase 1-like [Cicer arietinum] gi|502108374|ref|XP_004493454.1| | 19 | ||
| LjCkx8 | PREDICTED: cytokinin dehydrogenase 6-like [Glycine max] gi|356539470|ref|XP_003538221.1| | 23 | ||
| – | PREDICTED: reticuline oxidase-like protein-like [Glycine max] gi|356515398|ref|XP_003526387.1| | 20 | ||
| LjCkx6 | PREDICTED: cytokinin dehydrogenase 6-like [Glycine max] gi|356542934|ref|XP_003539919.1| | 23 | ||
| LjCkx1 | PREDICTED: cytokinin dehydrogenase 1-like [Cicer arietinum] gi|502108374|ref|XP_004493454.1| | 19 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: cytokinin dehydrogenase 5-like [Glycine max] gi|356509660|ref|XP_003523564.1| | 17 | ||
| LjCkx5 | PREDICTED: LOW QUALITY PROTEIN: cytokinin dehydrogenase 5-like [Glycine max] gi|356509660|ref|XP_003523564.1| | 25 | ||
| – | Cytokinin oxidase/dehydrogenase-like protein; TAIR: AT1G75450.1 cytokinin oxidase 5; Swiss-Prot: sp|Q67YU0|CKX5_ARATH Cytokinin dehydrogenase 5; TrEMBL-Plants: tr|A0A0U2UUJ0|A0A0U2UUJ0_LOTJA Cytokinin oxidase/dehydrogenase 5; Found in the gene: LotjaGi1g1v0423200 | 26 | ||
| – | Cytokinin oxidase/dehydrogenase-like protein; TAIR: AT2G41510.1 cytokinin oxidase/dehydrogenase 1; Swiss-Prot: sp|O22213|CKX1_ARATH Cytokinin dehydrogenase 1; TrEMBL-Plants: tr|A0A0U2UHS9|A0A0U2UHS9_LOTJA Cytokinin oxidase/dehydrogenase 1; Found in the gene: LotjaGi1g1v0669700 | 20 | ||
| – | Cytokinin oxidase/dehydrogenase-like protein; TAIR: AT3G63440.1 cytokinin oxidase/dehydrogenase 6; Swiss-Prot: sp|Q9LY71|CKX6_ARATH Cytokinin dehydrogenase 6; TrEMBL-Plants: tr|A0A0U2VEG5|A0A0U2VEG5_LOTJA Cytokinin oxidase/dehydrogenase 8; Found in the gene: LotjaGi3g1v0117100 | 24 | ||
| – | FAD-binding Berberine family protein, putative; TAIR: AT4G20860.1 FAD-binding Berberine family protein; Swiss-Prot: sp|Q9SUC6|BBE22_ARATH Berberine bridge enzyme-like 22; TrEMBL-Plants: tr|I1KFV4|I1KFV4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0331500 | 23 | ||
| – | Cytokinin oxidase/dehydrogenase-like protein; TAIR: AT3G63440.1 cytokinin oxidase/dehydrogenase 6; Swiss-Prot: sp|Q9LY71|CKX6_ARATH Cytokinin dehydrogenase 6; TrEMBL-Plants: tr|A0A0U2T9H6|A0A0U2T9H6_LOTJA Cytokinin oxidase/dehydrogenase 6; Found in the gene: LotjaGi3g1v0546100 | 24 | ||
| – | Cytokinin oxidase/dehydrogenase-like protein; TAIR: AT5G56970.1 cytokinin oxidase 3; Swiss-Prot: sp|Q9LTS3|CKX3_ARATH Cytokinin dehydrogenase 3; TrEMBL-Plants: tr|H7BRI4|H7BRI4_SOYBN Cytokinin dehydrogenase 3; Found in the gene: LotjaGi4g1v0310100 | 20 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF56176 | SUPERFAMILY | 1 | 7.69 |