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IPR006148

Source: InterPro

Description

IPR006148 is a Glucosamine/galactosamine-6-phosphate isomerase.

<p>This domain is characteristic of the enzymes 6-phosphogluconolactonase ([ec:3.1.1.31]), Glucosamine-6-phosphate isomerase ([ec:3.5.99.6]), and Galactosamine-6-phosphate isomerase. 6-Phosphogluconolactonase is the enzyme responsible for the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, the second step in the pentose phosphate pathway. Glucosamine-6-phosphate isomerase (or Glucosamine 6-phosphate deaminase) is the enzyme responsible for the conversion of D-glucosamine 6-phosphate into D-fructose 6-phosphate [[cite:PUB00005253]]. It is the last specific step in the pathway for N-acetylglucosamine (GlcNAC) utilization in bacteria such as Escherichia coli (gene nagB) or in fungi such as Candida albicans (gene NAG1).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005975
Biological process Carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
Subterm of

Associated Lotus transcripts 15

Transcript Name Description Predicted domains Domain count
Lj0g3v0226179.1
– PREDICTED: probable 6-phosphogluconolactonase 4, chloroplastic-like [Glycine max] gi|356551540|ref|XP_003544132.1|
Domains
15
Lj1g3v0948710.1
– PREDICTED: probable 6-phosphogluconolactonase 4, chloroplastic-like [Cicer arietinum] gi|502124145|ref|XP_004498405.1|
Domains
14
Lj1g3v1034270.1
– 6-phosphogluconolactonase [Medicago truncatula] gi|357464071|ref|XP_003602317.1|
Domains
9
Lj1g3v1034270.2
– 6-phosphogluconolactonase [Medicago truncatula] gi|357464071|ref|XP_003602317.1|
Domains
9
Lj1g3v1034290.1
– 6-phosphogluconolactonase [Medicago truncatula] gi|357464071|ref|XP_003602317.1|
Domains
9
Lj2g3v1242260.1
– PREDICTED: probable 6-phosphogluconolactonase 2-like [Glycine max] gi|356499907|ref|XP_003518777.1|
Domains
10
Lj2g3v1242260.2
– PREDICTED: probable 6-phosphogluconolactonase 2-like [Glycine max] gi|356499907|ref|XP_003518777.1|
Domains
9
LotjaGi1g1v0172500.1
– Glucosamine-6-phosphate deaminase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|I1MAJ4|I1MAJ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0172500
Domains
17
LotjaGi1g1v0172600.1
– Glucosamine-6-phosphate deaminase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|A0A072VQL3|A0A072VQL3_MEDTR Glucosamine-6-phosphate isomerase/6-phosphogluconolactonase; Found in the gene: LotjaGi1g1v0172600
Domains
16
LotjaGi1g1v0293300.5
– Glucosamine-6-phosphate deaminase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|G7J870|G7J870_MEDTR Glucosamine-6-phosphate isomerase/6-phosphogluconolactonase; Found in the gene: LotjaGi1g1v0293300
Domains
11
LotjaGi1g1v0293300.6
– Glucosamine-6-phosphate deaminase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|G7J870|G7J870_MEDTR Glucosamine-6-phosphate isomerase/6-phosphogluconolactonase; Found in the gene: LotjaGi1g1v0293300
Domains
11
LotjaGi1g1v0293300.7
– Glucosamine-6-phosphate deaminase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|G7J870|G7J870_MEDTR Glucosamine-6-phosphate isomerase/6-phosphogluconolactonase; Found in the gene: LotjaGi1g1v0293300
Domains
11
LotjaGi1g1v0293400_LC.1
– Glucosamine-6-phosphate deaminase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|A0A151RS78|A0A151RS78_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0293400_LC
Domains
8
LotjaGi1g1v0293500_LC.1
– 6-phosphogluconolactonase; TAIR: AT5G24400.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|A2Z3C4|6PGL4_ORYSI Probable 6-phosphogluconolactonase 4, chloroplastic; TrEMBL-Plants: tr|I3S2J6|I3S2J6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0293500_LC
Domains
6
LotjaGi2g1v0293100.1
– Glucosamine-6-phosphate deaminase; TAIR: AT1G13700.1 6-phosphogluconolactonase 1; Swiss-Prot: sp|A2YNH4|6PGL2_ORYSI Probable 6-phosphogluconolactonase 2; TrEMBL-Plants: tr|I3SB96|I3SB96_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0293100
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01400 CDD 1 6.67