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IPR007177

Source: InterPro

Description

IPR007177 is a 16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal.

<p>This domain can be found in the eukaryotic ribosome biogenesis protein Tsr3, which is involved in ribosomal RNA biogenesis [[cite:PUB00076727]]. This domain is also found in the C terminus of Tsr3 homologues from archaea. It is usually associated with a putative metal-binding region in RNase L inhibitor, RLI ([interpro:IPR007209]).</p> <p>Tsr3 from fungi and animals are responsible for 18S rRNA hypermodification. The Crystal structure of archaeal Tsr3 homologues revealed the same fold as in SPOUT-class RNA-methyltransferases but a distinct SAM binding mode. This unique SAM binding mode explains why Tsr3 transfers the acp and not the methyl group of SAM to its substrate. Structurally, Tsr3 therefore represents a novel class of acp transferase enzymes [[cite:PUB00094251]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj0g3v0188359.2
– PREDICTED: probable ribosome biogenesis protein C16orf42 homolog [Glycine max] gi|356525511|ref|XP_003531368.1|
Domains
9
LotjaGi4g1v0401100.2
– Ribosome biogenesis protein TSR3-like protein; TAIR: AT5G10070.2 RNase L inhibitor protein-like protein; Swiss-Prot: sp|Q5HZH2|TSR3_MOUSE Ribosome biogenesis protein TSR3 homolog; TrEMBL-Plants: tr|I1KT68|I1KT68_SOYBN Probable ribosome biogenesis protein GLYMA_08G139500; Found in the gene: LotjaGi4g1v0401100
Domains
8

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00