Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR007209 is a RNase L inhibitor RLI-like, possible metal-binding domain.
<p>This is part of a possible metal-binding domain in endoribonuclease RNase L inhibitor. It is found at the N-terminal end of RNase L inhibitor proteins, adjacent to the 4Fe-4S binding domain, [interpro:IPR017896]. Also often found adjacent to [interpro:IPR007177] in uncharacterised proteins. The RNase L system plays a major role in the anti-viral and anti-proliferative activities of interferons [[cite:PUB00009821]]. It is a component of the multifactor complex (MFC) involved in translation initiation and it is required for the processing and nuclear export of the 60S and 40S ribosomal subunits, playing a role in ribosome biogenesis [[cite:PUB00096731], [cite:PUB00045430]. Inhibitory activity requires concentration-dependent association of RLI with RNase L [[cite:PUB00009822]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable ribosome biogenesis protein C16orf42 homolog [Glycine max] gi|356525511|ref|XP_003531368.1| | 9 | ||
| – | PREDICTED: ABC transporter E family member 2-like [Cicer arietinum] gi|502161914|ref|XP_004512327.1| | 25 | ||
| – | ABC(ATP-binding) family transporter; TAIR: AT4G19210.1 RNAse l inhibitor protein 2; Swiss-Prot: sp|Q8LPJ4|AB2E_ARATH ABC transporter E family member 2; TrEMBL-Plants: tr|A0A0L9URH1|A0A0L9URH1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0349000 | 25 | ||
| – | ABC(ATP-binding) family transporter; TAIR: AT4G19210.1 RNAse l inhibitor protein 2; Swiss-Prot: sp|Q8LPJ4|AB2E_ARATH ABC transporter E family member 2; TrEMBL-Plants: tr|A0A0L9URH1|A0A0L9URH1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0349000 | 25 | ||
| – | ABC(ATP-binding) family transporter; TAIR: AT4G19210.1 RNAse l inhibitor protein 2; Swiss-Prot: sp|Q8LPJ4|AB2E_ARATH ABC transporter E family member 2; TrEMBL-Plants: tr|A0A0L9URH1|A0A0L9URH1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0349000 | 25 | ||
| – | Ribosome biogenesis protein TSR3-like protein; TAIR: AT5G10070.2 RNase L inhibitor protein-like protein; Swiss-Prot: sp|Q5HZH2|TSR3_MOUSE Ribosome biogenesis protein TSR3 homolog; TrEMBL-Plants: tr|I1KT68|I1KT68_SOYBN Probable ribosome biogenesis protein GLYMA_08G139500; Found in the gene: LotjaGi4g1v0401100 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |