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IPR022968 is a 16S/18S rRNA aminocarboxypropyltransferase Tsr3.
<p>This entry represents18S rRNA aminocarboxypropyltransferases Tsr3 and its homologues. Tsr3 from fungi and animals are responsible for 18S rRNA hypermodification. It introduces the acp group to the hypermodified m1acp3psi nucleotide at position 1191 (yeast)/ 1248 (humans) of 18S rRNA. The crystal structure of archaeal Tsr3 homologues revealed the same fold as in SPOUT-class RNA-methyltransferases but a distinct SAM binding mode. This unique SAM binding mode explains why Tsr3 transfers the acp and not the methyl group of SAM to its substrate. Structurally, Tsr3 therefore represents a novel class of acp transferase enzymes [[cite:PUB00094251]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable ribosome biogenesis protein C16orf42 homolog [Glycine max] gi|356525511|ref|XP_003531368.1| | 9 | ||
| – | Ribosome biogenesis protein TSR3-like protein; TAIR: AT5G10070.2 RNase L inhibitor protein-like protein; Swiss-Prot: sp|Q5HZH2|TSR3_MOUSE Ribosome biogenesis protein TSR3 homolog; TrEMBL-Plants: tr|I1KT68|I1KT68_SOYBN Probable ribosome biogenesis protein GLYMA_08G139500; Found in the gene: LotjaGi4g1v0401100 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |