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IPR007319 is a Small-subunit processome, Utp21.
<p>A large ribonuclear protein complex is required for the processing of the small-ribosomal-subunit rRNA -the small-subunit (SSU) processome [[cite:PUB00008496], [cite:PUB00035836]]. This preribosomal complex contains the U3 snoRNA and at least 40 proteins, which have the following properties:</p> <ul> <li>They are nucleolar.</li> <li>They are able to coimmunoprecipitate with the U3 snoRNA and Mpp10 (a protein specific to the SSU processome).</li> <li>They are required for 18S rRNA biogenesis.</li> </ul> <p>There appears to be a linkage between polymerase I transcription and the formation of the SSU processome; as some, but not all, of the SSU processome components are required for pre-rRNA transcription initiation. These SSU processome components have been termed t-Utps. They form a pre-complex with pre-18S rRNA in the absence of snoRNA U3 and other SSU processome components. It has been proposed that the t-Utp complex proteins are both rDNA and rRNA binding proteins that are involved in the initiation of pre18S rRNA transcription. Initially binding to rDNA then associating with the 5' end of the nascent pre18S rRNA. The t-Utpcomplex forms the nucleus around which the rest of the SSU processome components, including snoRNA U3, assemble [[cite:PUB00035837]]. From electron microscopy the SSU processome may correspond to the terminal knobs visualised at the 5' ends of nascent 18S rRNA.</p> <p>Utp21 is a component of the SSU processome, which is required for pre-18S rRNA processing. It interacts with Utp18 [[cite:PUB00035836]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | RRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. | ||
| Cellular component | Small-subunit processome | A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: WD repeat-containing protein 36-like [Glycine max] gi|356527435|ref|XP_003532316.1| | 17 | ||
| – | PREDICTED: WD repeat-containing protein 36-like [Glycine max] gi|356527435|ref|XP_003532316.1| | 15 | ||
| – | WD40 repeat-like protein; TAIR: AT4G04940.1 transducin family protein / WD-40 repeat family protein; Swiss-Prot: sp|O14053|UTP21_SCHPO U3 small nucleolar RNA-associated protein 21 homolog; TrEMBL-Plants: tr|A0A0S3TD02|A0A0S3TD02_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0234900 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |