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IPR008076 is a Cyanate hydratase.
<p>Cyanate hydratase or cyanase lyase catalyses the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide, allowing the host organisms to overcome the toxicity of environmental cyanate [[cite:PUB00010276]]. The enzyme is also known as cyanate lyase and cyanate hydrolase.</p> <p>The cyanate lyase monomer is composed of two domains: an N-terminal domain that shows structural similarity to the DNA-binding α-helix bundle motif, and a C-terminal domain that has an 'open fold' that shows no structural similarity to other proteins [[cite:PUB00010276]].</p> <p>The enzyme is active as a homodecamer of 17kDa subunits, and displays half-site binding of substrates or substrate analogues. The dimer structure reveals the C-terminal domains to be intertwined; the decamer is formed from a pentamer of these dimers. The active site of the enzyme is located between dimers and comprises residues from four adjacent subunits of the homodecamer.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Cyanate hydratase activity | Catalysis of the reaction: cyanate + H2O = carbamate. | ||
| Biological process | Cyanate metabolic process | The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: cyanate hydratase-like [Cicer arietinum] gi|502123007|ref|XP_004497968.1| | 16 | ||
| – | Cyanate hydratase; TAIR: AT3G23490.1 cyanase; Swiss-Prot: sp|B7FKW7|CYNS_MEDTR Cyanate hydratase; TrEMBL-Plants: tr|I3SSK7|I3SSK7_MEDTR Cyanate hydratase; Found in the gene: LotjaGi6g1v0004000 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00559 | CDD | 1 | 50.00 |