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IPR008808 is a Powdery mildew resistance protein, RPW8 domain.
<p>This entry represents the RPW8 domain found in several broad-spectrum mildew resistance proteins from Arabidopsis thaliana and other dicots. Plant disease resistance (R) genes control the recognition of specific pathogens and activate subsequent defence responses. The R protein-mediated defences typically involve a rapid, localized necrosis, or hypersensitive response (HR), at the site of infection, and the localised formation of antimicrobial chemicals and proteins that restrict growth of the pathogen. The A. thaliana locus Resistance to Powdery Mildew 8 (RPW8) contains two naturally polymorphic, dominant R genes: RPW8.1 and RPW8.2, which individually control resistance to a broad range of powdery mildew pathogens. They induce localised, salicylic acid-dependent defences similar to those induced by R genes that control specific resistance. Apparently, broad-spectrum resistance mediated by RPW8 uses the same mechanisms as specific resistance [[cite:PUB00011557], [cite:PUB00033612]]. RPW8.1 and RPW8.2 share similarity with an ~150 amino acid module forming the N terminus of a group of disease resistance proteins, which have a nucleotide-binding site (NBS) and leucine-rich repeats (LRRs) [[cite:PUB00011557], [cite:PUB00033612]].</p> <p>The RPW8 domain sequences contain a predicted N-terminal transmembrane (TM) region or possibly a signal peptide, and a coiled-coil (CC) motif [[cite:PUB00011557]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable disease resistance protein At5g66900-like [Glycine max] gi|356565670|ref|XP_003551061.1| | 14 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Vitis vinifera] gi|359480459|ref|XP_002265449.2| | 8 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Vitis vinifera] gi|359480459|ref|XP_002265449.2| | 5 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Vitis vinifera] gi|359480459|ref|XP_002265449.2| | 2 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Glycine max] gi|356495456|ref|XP_003516593.1| | 15 | ||
| – | PREDICTED: extended synaptotagmin-1-like isoform 2 [Glycine max] gi|356562955|ref|XP_003549733.1| | 12 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Glycine max] gi|356565670|ref|XP_003551061.1| | 10 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Cicer arietinum] gi|502160966|ref|XP_004511973.1| | 20 | ||
| – | PREDICTED: probable disease resistance protein At5g66900-like [Glycine max] gi|356565670|ref|XP_003551061.1| | 11 | ||
| – | PREDICTED: extended synaptotagmin-1-like isoform 2 [Glycine max] gi|356562955|ref|XP_003549733.1| | 12 | ||
| – | PREDICTED: extended synaptotagmin-1-like isoform 2 [Glycine max] gi|356562955|ref|XP_003549733.1| | 18 | ||
| – | PREDICTED: probable disease resistance protein At4g33300-like [Cicer arietinum] gi|502125876|ref|XP_004499098.1| | 14 | ||
| – | NBS-LRR disease resistance protein; TAIR: AT5G66900.1 Disease resistance protein (CC-NBS-LRR class) family; Swiss-Prot: sp|Q9FKZ1|DRL42_ARATH Probable disease resistance protein At5g66900; TrEMBL-Plants: tr|A0A072TSV7|A0A072TSV7_MEDTR LRR and NB-ARC domain disease resistance protein; Found in the gene: LotjaGi1g1v0033100 | 13 | ||
| – | NBS-LRR disease resistance protein; TAIR: AT5G66900.1 Disease resistance protein (CC-NBS-LRR class) family; Swiss-Prot: sp|Q9FKZ1|DRL42_ARATH Probable disease resistance protein At5g66900; TrEMBL-Plants: tr|W0M160|W0M160_CICAR NBS-LRR protein; Found in the gene: LotjaGi2g1v0398100 | 20 | ||
| – | NBS-LRR disease resistance protein; TAIR: AT5G66900.1 Disease resistance protein (CC-NBS-LRR class) family; Swiss-Prot: sp|Q9FKZ1|DRL42_ARATH Probable disease resistance protein At5g66900; TrEMBL-Plants: tr|A0A1J7FP49|A0A1J7FP49_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0108700 | 16 | ||
| – | NBS-LRR disease resistance protein; TAIR: AT5G66900.1 Disease resistance protein (CC-NBS-LRR class) family; Swiss-Prot: sp|Q9FKZ1|DRL42_ARATH Probable disease resistance protein At5g66900; TrEMBL-Plants: tr|A0A072TSV7|A0A072TSV7_MEDTR LRR and NB-ARC domain disease resistance protein; Found in the gene: LotjaGi4g1v0109300 | 13 | ||
| – | NBS-LRR disease resistance protein; TAIR: AT5G66900.1 Disease resistance protein (CC-NBS-LRR class) family; Swiss-Prot: sp|Q9FKZ1|DRL42_ARATH Probable disease resistance protein At5g66900; TrEMBL-Plants: tr|A0A072TSV7|A0A072TSV7_MEDTR LRR and NB-ARC domain disease resistance protein; Found in the gene: LotjaGi4g1v0109400 | 14 | ||
| – | Synaptotagmin-1; TAIR: AT5G11100.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|A0JJX5|SYT4_ARATH Synaptotagmin-4; TrEMBL-Plants: tr|A0A151SRE3|A0A151SRE3_CAJCA Extended synaptotagmin-3; Found in the gene: LotjaGi4g1v0278100_LC | 13 | ||
| – | Calcium lipid binding protein, putative; TAIR: AT1G05500.1 Calcium-dependent lipid-binding (CaLB domain) family protein; Swiss-Prot: sp|Q8L706|SYT5_ARATH Synaptotagmin-5; TrEMBL-Plants: tr|A0A151SRE3|A0A151SRE3_CAJCA Extended synaptotagmin-3; Found in the gene: LotjaGi4g1v0278500_LC | 19 | ||
| – | Disease resistance protein (NBS-LRR class) family; TAIR: AT4G33300.1 ADR1-like 1; Swiss-Prot: sp|Q9SZA7|DRL29_ARATH Probable disease resistance protein At4g33300; TrEMBL-Plants: tr|A0A151RMR8|A0A151RMR8_CAJCA Putative disease resistance protein family; Found in the gene: LotjaGi5g1v0023000 | 16 | ||
| – | Disease resistance protein (NBS-LRR class) family; TAIR: AT4G33300.1 ADR1-like 1; Swiss-Prot: sp|Q9SZA7|DRL29_ARATH Probable disease resistance protein At4g33300; TrEMBL-Plants: tr|G7I4I5|G7I4I5_MEDTR Disease resistance protein (CC-NBS-LRR class) family protein; Found in the gene: LotjaGi5g1v0023100 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF52540 | SUPERFAMILY | 1 | 4.76 |