Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR010036 is a Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type.
<p>This entry represents two closely related clades of sequences from eukaryotes and archaea, however, some uncharacterised bacterial sequences are also included in this family. The mouse enzyme has been characterised as a phosphatase and has been positively identified as a member of the haloacid dehalogenase (HAD) superfamily by site-directed mutagenesis of the active site residues [[cite:PUB00009589], [cite:PUB00013839]]. Its structure is similar to other HAD members but MDP-1 appears to be equally able to dephosphorylate phosphotyrosine and closed-ring phosphosugars [[cite:PUB00031695]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Phosphatase activity | Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Magnesium-dependent phosphatase [Medicago truncatula] gi|357476201|ref|XP_003608386.1| | 11 | ||
| – | Magnesium-dependent phosphatase [Medicago truncatula] gi|357445983|ref|XP_003593269.1| | 11 | ||
| – | Magnesium-dependent phosphatase 1; TAIR: AT2G14110.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q9D967|MGDP1_MOUSE Magnesium-dependent phosphatase 1; TrEMBL-Plants: tr|I3T080|I3T080_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0039200 | 14 | ||
| – | Magnesium-dependent phosphatase 1; TAIR: AT2G14110.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q9D967|MGDP1_MOUSE Magnesium-dependent phosphatase 1; TrEMBL-Plants: tr|I3T080|I3T080_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0039200 | 14 | ||
| – | Magnesium-dependent phosphatase 1; TAIR: AT2G14110.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q9D967|MGDP1_MOUSE Magnesium-dependent phosphatase 1; TrEMBL-Plants: tr|I3S090|I3S090_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0349400 | 14 | ||
| – | Magnesium-dependent phosphatase 1; TAIR: AT2G14110.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Swiss-Prot: sp|Q9D967|MGDP1_MOUSE Magnesium-dependent phosphatase 1; TrEMBL-Plants: tr|I3S090|I3S090_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0349400 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07501 | CDD | 1 | 16.67 |