Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR011014 is a Mechanosensitive ion channel MscS, transmembrane-2.
<p>MscS is a mechanosensitive channel present in the membrane of bacteria, archaea and eukarya that responds both to stretching of the cell membrane and to membrane depolarisation [[cite:PUB00013956], [cite:PUB00101037], [cite:PUB00064132], [cite:PUB00101036]]. MscS folds as a homo-heptamer with a cylindrical shape, and can be divided into transmembrane and extramembrane regions: an N-terminal periplasmic region, a transmembrane region, and a C-terminal cytoplasmic region. The MscS family of channels shows diversity in size and sequence between its members; most of the diversity occurs in the size of the transmembrane region, which ranges from three to eleven transmembrane helices, although the three C-terminal helices are conserved. This domain superfamily covers the core transmembrane region, which consists of three transmembrane helices per subunit in an oligomeric fold.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: mechanosensitive ion channel protein 1, mitochondrial-like [Cicer arietinum] gi|502157089|ref|XP_004510754.1| | 14 | ||
| – | PREDICTED: mechanosensitive ion channel protein 1, mitochondrial-like [Cicer arietinum] gi|502157089|ref|XP_004510754.1| | 11 | ||
| – | Mechanosensitive ion channel protein; TAIR: AT4G00290.1 Mechanosensitive ion channel protein; Swiss-Prot: sp|Q8VZL4|MSL1_ARATH Mechanosensitive ion channel protein 1, mitochondrial; TrEMBL-Plants: tr|A0A0S3SYM0|A0A0S3SYM0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0386200 | 15 | ||
| – | Mechanosensitive ion channel protein; TAIR: AT4G00290.1 Mechanosensitive ion channel protein; Swiss-Prot: sp|Q8VZL4|MSL1_ARATH Mechanosensitive ion channel protein 1, mitochondrial; TrEMBL-Plants: tr|A0A0S3SYM0|A0A0S3SYM0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0386200 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |