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IPR011065 is a Kunitz inhibitor STI-like superfamily.
<p>The Kunitz-type soybean trypsin inhibitor (STI) family consists mainly of proteinase inhibitors from Leguminosae seeds [[cite:PUB00014133]]. They belong to MEROPS inhibitor family I3, clan IC. They exhibit proteinase inhibitory activity against serine proteinases; trypsin (MEROPS peptidase family S1, [interpro:IPR001254]) and subtilisin (MEROPS peptidase family S8, [interpro:IPR000209]), thiol proteinases (MEROPS peptidase family C1, [interpro:IPR000668]) and aspartic proteinases (MEROPS peptidase family A1, [interpro:IPR001461]) [[cite:PUB00014133]]. STI has a beta-Trefoil type fold consisting of a closed barrel and a hairpin triplet, with internal pseudo threefold symmetry.</p> <p>The C-terminal domain of Clostridium spp. neurotoxins have an overfold that is very similar to that of the Kunitz STI family. The tetanus toxin binds to the gangliosides receptor, GT1b, and is composed of light and heavy chains, where the light chain is responsible for toxicity; the Kunitz-like domain is found on the C-terminal of the heavy chain, and is responsible for binding to sensitive cells [[cite:PUB00014264]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: miraculin-like [Glycine max] gi|356531028|ref|XP_003534080.1| | 12 | ||
– | PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| | 14 | ||
– | PREDICTED: miraculin-like [Glycine max] gi|356531028|ref|XP_003534080.1| | 14 | ||
– | PREDICTED: miraculin-like [Glycine max] gi|356531023|ref|XP_003534078.1| | 16 | ||
– | Kunitz-type trypsin inhibitor-like 1 protein [Medicago truncatula] gi|357498565|ref|XP_003619571.1| | 8 | ||
– | 21 kDa seed protein [Medicago truncatula] gi|357499767|ref|XP_003620172.1| | 13 | ||
– | Pathogen-inducible trypsin-inhibitor-like protein [Medicago truncatula] gi|357499791|ref|XP_003620184.1| | 18 | ||
– | Pathogen-inducible trypsin-inhibitor-like protein [Medicago truncatula] gi|357499773|ref|XP_003620175.1| | 17 | ||
– | Miraculin [Medicago truncatula] gi|357499797|ref|XP_003620187.1| | 18 | ||
– | PREDICTED: miraculin-like [Glycine max] gi|356531034|ref|XP_003534083.1| | 8 | ||
– | Pathogen-inducible trypsin-inhibitor-like protein [Medicago truncatula] gi|357499791|ref|XP_003620184.1| | 18 | ||
– | PREDICTED: miraculin-like [Glycine max] gi|356531023|ref|XP_003534078.1| | 15 | ||
– | PREDICTED: miraculin-like [Glycine max] gi|356531028|ref|XP_003534080.1| | 15 | ||
– | RecName: Full=Kunitz-type trypsin inhibitor-like 2 protein; AltName: Full=Protease inhibitor from pea 2; Flags: Precursorgi|3650368|emb|CAA09607.1| profucosidase [Pisum sativum] gi|75220301|sp|O82711.1|PIP22_PEA | 12 | ||
– | RecName: Full=Kunitz-type trypsin inhibitor-like 2 protein; AltName: Full=Protease inhibitor from pea 2; Flags: Precursorgi|3650368|emb|CAA09607.1| profucosidase [Pisum sativum] gi|75220301|sp|O82711.1|PIP22_PEA | 18 | ||
– | PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| | 14 | ||
– | PREDICTED: miraculin-like [Glycine max] gi|356531070|ref|XP_003534101.1| | 15 | ||
– | Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| | 17 | ||
– | Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| | 17 | ||
– | Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| | 15 | ||
– | Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| | 17 | ||
– | 17 | |||
– | PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| | 15 | ||
– | PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| | 16 | ||
– | RecName: Full=Kunitz-type trypsin inhibitor-like 1 protein; AltName: Full=Protease inhibitor from pea 1; Flags: Precursorgi|3859063|emb|CAA57931.1| alpha-fucosidase [Pisum sativum] gi|75102445|sp|Q41015.2|PIP21_PEA | 17 | ||
– | RecName: Full=Kunitz-type trypsin inhibitor-like 1 protein; AltName: Full=Protease inhibitor from pea 1; Flags: Precursorgi|3859063|emb|CAA57931.1| alpha-fucosidase [Pisum sativum] gi|75102445|sp|Q41015.2|PIP21_PEA | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|P83667|DRTI_DELRE Kunitz-type serine protease inhibitor DrTI; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0289000 | 14 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0100200 | 15 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P83667|DRTI_DELRE Kunitz-type serine protease inhibitor DrTI; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0131200_LC | 8 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3SLI3|I3SLI3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161400 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161500 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3S0E9|I3S0E9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0163300 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3S844|I3S844_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0163500 | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3SA98|I3SA98_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0163700 | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|A0A1J7GXD8|A0A1J7GXD8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0164500_LC | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3SLI3|I3SLI3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0165200 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SYF1|I3SYF1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0175900 | 8 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3S2I3|I3S2I3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176200 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3S2I3|I3S2I3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176300 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|A0A0L9VIS0|A0A0L9VIS0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0176600 | 14 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|I3SMN8|I3SMN8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176700 | 14 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SMN8|I3SMN8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176900 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|A0A0D2RWN2|A0A0D2RWN2_GOSRA Uncharacterized protein; Found in the gene: LotjaGi2g1v0177000 | 17 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|A0A151TWH0|A0A151TWH0_CAJCA Miraculin; Found in the gene: LotjaGi2g1v0177200 | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|A0A151TWH0|A0A151TWH0_CAJCA Miraculin; Found in the gene: LotjaGi2g1v0177300 | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|A0A0L9VHR8|A0A0L9VHR8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0177400 | 17 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0177500_LC | 16 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0177800 | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0178000 | 14 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0178600 | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0284900 | 14 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P29421|IAAS_ORYSJ Alpha-amylase/subtilisin inhibitor; TrEMBL-Plants: tr|I3S3Q9|I3S3Q9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0038800 | 18 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|Q41015|PIP21_PEA Kunitz-type trypsin inhibitor-like 1 protein; TrEMBL-Plants: tr|I3SLI3|I3SLI3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0005100 | 15 | ||
– | Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q41015|PIP21_PEA Kunitz-type trypsin inhibitor-like 1 protein; TrEMBL-Plants: tr|I3T9S8|I3T9S8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0085800 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd00178 | CDD | 1 | 1.85 |