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IPR011065

Description

IPR011065 is a Kunitz inhibitor STI-like superfamily.

<p>The Kunitz-type soybean trypsin inhibitor (STI) family consists mainly of proteinase inhibitors from Leguminosae seeds [[cite:PUB00014133]]. They belong to MEROPS inhibitor family I3, clan IC. They exhibit proteinase inhibitory activity against serine proteinases; trypsin (MEROPS peptidase family S1, [interpro:IPR001254]) and subtilisin (MEROPS peptidase family S8, [interpro:IPR000209]), thiol proteinases (MEROPS peptidase family C1, [interpro:IPR000668]) and aspartic proteinases (MEROPS peptidase family A1, [interpro:IPR001461]) [[cite:PUB00014133]]. STI has a beta-Trefoil type fold consisting of a closed barrel and a hairpin triplet, with internal pseudo threefold symmetry.</p> <p>The C-terminal domain of Clostridium spp. neurotoxins have an overfold that is very similar to that of the Kunitz STI family. The tetanus toxin binds to the gangliosides receptor, GT1b, and is composed of light and heavy chains, where the light chain is responsible for toxicity; the Kunitz-like domain is found on the C-terminal of the heavy chain, and is responsible for binding to sensitive cells [[cite:PUB00014264]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 54

Transcript Name Description Predicted domains Domain count
PREDICTED: miraculin-like [Glycine max] gi|356531028|ref|XP_003534080.1| 12
PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| 14
PREDICTED: miraculin-like [Glycine max] gi|356531028|ref|XP_003534080.1| 14
PREDICTED: miraculin-like [Glycine max] gi|356531023|ref|XP_003534078.1| 16
Kunitz-type trypsin inhibitor-like 1 protein [Medicago truncatula] gi|357498565|ref|XP_003619571.1| 8
21 kDa seed protein [Medicago truncatula] gi|357499767|ref|XP_003620172.1| 13
Pathogen-inducible trypsin-inhibitor-like protein [Medicago truncatula] gi|357499791|ref|XP_003620184.1| 18
Pathogen-inducible trypsin-inhibitor-like protein [Medicago truncatula] gi|357499773|ref|XP_003620175.1| 17
Miraculin [Medicago truncatula] gi|357499797|ref|XP_003620187.1| 18
PREDICTED: miraculin-like [Glycine max] gi|356531034|ref|XP_003534083.1| 8
Pathogen-inducible trypsin-inhibitor-like protein [Medicago truncatula] gi|357499791|ref|XP_003620184.1| 18
PREDICTED: miraculin-like [Glycine max] gi|356531023|ref|XP_003534078.1| 15
PREDICTED: miraculin-like [Glycine max] gi|356531028|ref|XP_003534080.1| 15
RecName: Full=Kunitz-type trypsin inhibitor-like 2 protein; AltName: Full=Protease inhibitor from pea 2; Flags: Precursorgi|3650368|emb|CAA09607.1| profucosidase [Pisum sativum] gi|75220301|sp|O82711.1|PIP22_PEA 12
RecName: Full=Kunitz-type trypsin inhibitor-like 2 protein; AltName: Full=Protease inhibitor from pea 2; Flags: Precursorgi|3650368|emb|CAA09607.1| profucosidase [Pisum sativum] gi|75220301|sp|O82711.1|PIP22_PEA 18
PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| 14
PREDICTED: miraculin-like [Glycine max] gi|356531070|ref|XP_003534101.1| 15
Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| 17
Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| 17
Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| 15
Protease inhibitor [Sesbania rostrata] gi|20269067|emb|CAD29731.1| 17
17
PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| 15
PREDICTED: kunitz-type trypsin inhibitor-like 2 protein-like [Glycine max] gi|356577967|ref|XP_003557092.1| 16
RecName: Full=Kunitz-type trypsin inhibitor-like 1 protein; AltName: Full=Protease inhibitor from pea 1; Flags: Precursorgi|3859063|emb|CAA57931.1| alpha-fucosidase [Pisum sativum] gi|75102445|sp|Q41015.2|PIP21_PEA 17
RecName: Full=Kunitz-type trypsin inhibitor-like 1 protein; AltName: Full=Protease inhibitor from pea 1; Flags: Precursorgi|3859063|emb|CAA57931.1| alpha-fucosidase [Pisum sativum] gi|75102445|sp|Q41015.2|PIP21_PEA 18
Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|P83667|DRTI_DELRE Kunitz-type serine protease inhibitor DrTI; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0289000 14
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0100200 15
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P83667|DRTI_DELRE Kunitz-type serine protease inhibitor DrTI; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0131200_LC 8
Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3SLI3|I3SLI3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161400 16
Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161500 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3S0E9|I3S0E9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0163300 16
Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3S844|I3S844_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0163500 18
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3SA98|I3SA98_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0163700 18
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|A0A1J7GXD8|A0A1J7GXD8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0164500_LC 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3SLI3|I3SLI3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0165200 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SYF1|I3SYF1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0175900 8
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3S2I3|I3S2I3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176200 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3S2I3|I3S2I3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176300 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|A0A0L9VIS0|A0A0L9VIS0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0176600 14
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|I3SMN8|I3SMN8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176700 14
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SMN8|I3SMN8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0176900 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|A0A0D2RWN2|A0A0D2RWN2_GOSRA Uncharacterized protein; Found in the gene: LotjaGi2g1v0177000 17
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|A0A151TWH0|A0A151TWH0_CAJCA Miraculin; Found in the gene: LotjaGi2g1v0177200 18
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|A0A151TWH0|A0A151TWH0_CAJCA Miraculin; Found in the gene: LotjaGi2g1v0177300 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P13087|MIRA_SYNDU Miraculin; TrEMBL-Plants: tr|A0A0L9VHR8|A0A0L9VHR8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0177400 17
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0177500_LC 16
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0177800 18
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0178000 14
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q9LMU2|KTI2_ARATH Kunitz trypsin inhibitor 2; TrEMBL-Plants: tr|I3SHS0|I3SHS0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0178600 18
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|O82711|PIP22_PEA Kunitz-type trypsin inhibitor-like 2 protein; TrEMBL-Plants: tr|I3T863|I3T863_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0284900 14
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|P29421|IAAS_ORYSJ Alpha-amylase/subtilisin inhibitor; TrEMBL-Plants: tr|I3S3Q9|I3S3Q9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0038800 18
Kunitz trypsin inhibitor; TAIR: AT1G73260.1 kunitz trypsin inhibitor 1; Swiss-Prot: sp|Q41015|PIP21_PEA Kunitz-type trypsin inhibitor-like 1 protein; TrEMBL-Plants: tr|I3SLI3|I3SLI3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0005100 15
Kunitz trypsin inhibitor; TAIR: AT1G17860.1 Kunitz family trypsin and protease inhibitor protein; Swiss-Prot: sp|Q41015|PIP21_PEA Kunitz-type trypsin inhibitor-like 1 protein; TrEMBL-Plants: tr|I3T9S8|I3T9S8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0085800 19

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00178 CDD 1 1.85