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IPR011273

Source: InterPro

Description

IPR011273 is a Malate dehydrogenase, NADP-dependent, plants.

<p>This entry represents the NADP-dependent malate dehydrogenase found in plants, mosses and green algae and localised to the chloroplast. Malate dehydrogenase converts oxaloacetate into malate, a critical step in the C4 cycle which allows circumvention of the effects of photorespiration. Malate is subsequently transported from the chloroplast to the cytoplasm (and then to the bundle sheath cells in C4 plants). The plant and moss enzymes are light regulated via cysteine diisulphide bonds. The enzyme from sorghum has been crystallised [[cite:PUB00013757]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006108
Biological process Malate metabolic process The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
Subterm of
GO:0046554
Molecular function Malate dehydrogenase (NADP+) activity Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.
Subterm of
GO:0055114
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi5g1v0254100.1
– Malate dehydrogenase; TAIR: AT5G58330.2 lactate/malate dehydrogenase family protein; Swiss-Prot: sp|O48902|MDHP_MEDSA Malate dehydrogenase [NADP], chloroplastic; TrEMBL-Plants: tr|A0A0R0HW29|A0A0R0HW29_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0254100
Domains
19

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01338 CDD 1 100.00