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IPR013792

Description

IPR013792 is a RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta.

<p>This superfamily represents an α/β domain consisting of alternating β-strands and α helices in two layer. This domain is found in RNA 3'-terminal phosphate cyclase (RPTC), where it occurs as a duplication of three repeats of this fold packed together around a pseudo three-fold axis [[cite:PUB00006476]]. RNA cyclases are a family of RNA-modifying enzymes that catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA. These cyclases contain an insert α/β domain with a thioredoxin topology ([interpro:IPR013791]).</p> <p>This domain is also found in enolpyruvate transferase, where it occurs as a duplication of six repeats of this fold organised into two RPTC-like domains [[cite:PUB00028019], [cite:PUB00028020]]. Enolpyruvate transferase is the first enzyme in bacterial peptidoglycan biosynthesis, catalysing the transfer of enolpyruvate from phosphoenolpyruvate to UDP-N-acetyl-glucosamine.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

Associated Lotus transcripts 11

Transcript Name Description Predicted domains Domain count
PREDICTED: LOW QUALITY PROTEIN: probable RNA 3'-terminal phosphate cyclase-like protein-like [Glycine max] gi|356496398|ref|XP_003517055.1| 20
PREDICTED: LOW QUALITY PROTEIN: probable RNA 3'-terminal phosphate cyclase-like protein-like [Glycine max] gi|356496398|ref|XP_003517055.1| 21
PREDICTED: LOW QUALITY PROTEIN: probable RNA 3'-terminal phosphate cyclase-like protein-like [Glycine max] gi|356496398|ref|XP_003517055.1| 21
3-phosphoshikimate 1-carboxyvinyltransferase [Medicago truncatula] gi|357469709|ref|XP_003605139.1| 15
3-phosphoshikimate 1-carboxyvinyltransferase [Medicago truncatula] gi|357469709|ref|XP_003605139.1| 15
RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 23
RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 23
RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 17
RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 23
RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0193200 23
3-phosphoshikimate 1-carboxyvinyltransferase; TAIR: AT2G45300.1 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta; Swiss-Prot: sp|P11043|AROA_PETHY 3-phosphoshikimate 1-carboxyvinyltransferase, chloroplastic; TrEMBL-Plants: tr|A0A1J7H2T7|A0A1J7H2T7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0434500 16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 9.09