Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR020719 is a RNA 3'-terminal phosphate cyclase-like, conserved site.
<p>RNA cyclases are a family of RNA-modifying enzymes that are conserved in eukaryotes, bacteria and archaea. Type 1 RNA 3'-terminal phosphate cyclases ([ec:6.5.1.4]) [[cite:PUB00001300], [cite:PUB00003565]] catalyse the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA:</p> <p><reaction> ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate </reaction></p> <p>The physiological function of the cyclase is not known, but the enzyme could be involved in the maintenance of cyclic ends in tRNA splicing intermediates or in the cyclisation of the 3' end of U6 snRNA [[cite:PUB00001300]].</p> <p>A second subfamily of RNA 3'-terminal phosphate cyclases (type 2) that do not have cyclase activity have been identified in eukaryotes. They are localised to the nucleolus and are involved in ribosomal modification [[cite:PUB00042947]].</p> <p>RNA 3'-terminal phosphate cyclases contain a conserved glycine-rich stretch of residues located in the central part of the sequence, which is reminiscent of various ATP, GTP or AMP glycine-rich loops, and may be involved in AMP binding. This entry represents the conserved site.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: LOW QUALITY PROTEIN: probable RNA 3'-terminal phosphate cyclase-like protein-like [Glycine max] gi|356496398|ref|XP_003517055.1| | 20 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: probable RNA 3'-terminal phosphate cyclase-like protein-like [Glycine max] gi|356496398|ref|XP_003517055.1| | 21 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: probable RNA 3'-terminal phosphate cyclase-like protein-like [Glycine max] gi|356496398|ref|XP_003517055.1| | 21 | ||
| – | RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 | 23 | ||
| – | RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 | 23 | ||
| – | RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 | 17 | ||
| – | RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0126600 | 23 | ||
| – | RNA 3-terminal phosphate cyclase-like protein, putative; TAIR: AT5G22100.1 RNA cyclase family protein; Swiss-Prot: sp|Q9C578|RCL1_ARATH Probable RNA 3'-terminal phosphate cyclase-like protein; TrEMBL-Plants: tr|A0A151S8V9|A0A151S8V9_CAJCA Putative RNA 3'-terminal phosphate cyclase-like protein; Found in the gene: LotjaGi2g1v0193200 | 23 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00875 | CDD | 1 | 12.50 |