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IPR013881 is a Pre-mRNA-splicing factor 3 domain.
<p>This entry represents a domain that is located centrally in mammal U4/U6 small nuclear ribonucleoprotein Prp3 and Protein RDM16 from Arabidopsis thaliana and towards the N-terminal end in Prp3 from yeast.</p> <p>Pre-mRNA processing factor 3 (PRP3) is a U4/U6-associated splicing factor. It plays a key role in the recognition of the snRNA duplex. Defects in PRPF3 are the cause of retinitis pigmentosa type 18 (RP18). RP leads to degeneration of retinal photoreceptor cells [[cite:PUB00033315], [cite:PUB00062917], [cite:PUB00062918]]. In Arabidposis thaliana, protein RDM16 acts as a pre-mRNA splicing factor and functions in RNA-directed DNA methylation by influencing Pol V transcript levels [[cite:PUB00083217]].</p> <p>This domain shows an α-helical structure [[cite:PUB00100667]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp3-like [Glycine max] gi|356495750|ref|XP_003516736.1| | 8 | ||
| – | U4/U6 small nuclear ribonucleoprotein Prp3; TAIR: AT1G28060.1 Pre-mRNA-splicing factor 3; Swiss-Prot: sp|Q9C7E7|RDM16_ARATH Protein RDM16; TrEMBL-Plants: tr|I1JAI8|I1JAI8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0359600 | 8 | ||
| – | U4/U6 small nuclear ribonucleoprotein Prp3; TAIR: AT1G28060.1 Pre-mRNA-splicing factor 3; Swiss-Prot: sp|Q9C7E7|RDM16_ARATH Protein RDM16; TrEMBL-Plants: tr|A0A151SCZ2|A0A151SCZ2_CAJCA U4/U6 small nuclear ribonucleoprotein Prp3; Found in the gene: LotjaGi5g1v0359600 | 8 | ||
| – | U4/U6 small nuclear ribonucleoprotein Prp3; TAIR: AT1G28060.1 Pre-mRNA-splicing factor 3; Swiss-Prot: sp|Q9C7E7|RDM16_ARATH Protein RDM16; TrEMBL-Plants: tr|A0A151SCZ2|A0A151SCZ2_CAJCA U4/U6 small nuclear ribonucleoprotein Prp3; Found in the gene: LotjaGi5g1v0359600 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |