Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR027104 is a U4/U6 small nuclear ribonucleoprotein Prp3.
<p>Prp3 (also known as PRP3) participates in pre-mRNA splicing [[cite:PUB00063460]]. It may play a role in the assembly of the U4/U5/U6 tri-snRNP complex [[cite:PUB00062916]]. Defects in PRPF3 are the cause of retinitis pigmentosa type 18 (RP18). RP leads to degeneration of retinal photoreceptor cells [[cite:PUB00033315], [cite:PUB00062917], [cite:PUB00062918]]. In<i>Arabidposis thaliana</i>, protein RDM16 acts as a pre-mRNA splicing factor and functions in RNA-directed DNA methylation by influencing Pol V transcript levels [[cite:PUB00083217]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | MRNA splicing, via spliceosome | The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. | ||
| Cellular component | U4/U6 x U5 tri-snRNP complex | A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp3-like [Glycine max] gi|356495750|ref|XP_003516736.1| | 8 | ||
| – | U4/U6 small nuclear ribonucleoprotein Prp3; TAIR: AT1G28060.1 Pre-mRNA-splicing factor 3; Swiss-Prot: sp|Q9C7E7|RDM16_ARATH Protein RDM16; TrEMBL-Plants: tr|I1JAI8|I1JAI8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0359600 | 8 | ||
| – | U4/U6 small nuclear ribonucleoprotein Prp3; TAIR: AT1G28060.1 Pre-mRNA-splicing factor 3; Swiss-Prot: sp|Q9C7E7|RDM16_ARATH Protein RDM16; TrEMBL-Plants: tr|A0A151SCZ2|A0A151SCZ2_CAJCA U4/U6 small nuclear ribonucleoprotein Prp3; Found in the gene: LotjaGi5g1v0359600 | 8 | ||
| – | U4/U6 small nuclear ribonucleoprotein Prp3; TAIR: AT1G28060.1 Pre-mRNA-splicing factor 3; Swiss-Prot: sp|Q9C7E7|RDM16_ARATH Protein RDM16; TrEMBL-Plants: tr|A0A151SCZ2|A0A151SCZ2_CAJCA U4/U6 small nuclear ribonucleoprotein Prp3; Found in the gene: LotjaGi5g1v0359600 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |