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IPR015007

Source: InterPro

Description

IPR015007 is a Nuclear pore complex, NUP2/50/61.

<p>This entry represents a domain found in Nup2, 50 and 61, which are components of the nuclear pore complex.</p> <p>NUP2 encodes a non-essential nuclear pore protein that has a central domain similar to those of Nsp1 and Nup1[[cite:PUB00053733], [cite:PUB00019946]]. Transport of macromolecules between the nucleus and the cytoplasm of eukaryotic cells occurs through the nuclear pore complex (NPC), a large macromolecular complex that spans the nuclear envelope [[cite:PUB00019946], [cite:PUB00053734], [cite:PUB00053735]]. The structure of the vertebrate NPC has been studied extensively; recent reviews include [[cite:PUB00053736], [cite:PUB00053737], [cite:PUB00053738], [cite:PUB00053739]]. The yeast NPC shares several features with the vertebrate NPC, despite being smaller and less elaborate [[cite:PUB00053740], [cite:PUB00053741]]. Many yeast nuclear pore proteins, or nucleoporins, have been identified by a variety of genetic approaches [[cite:PUB00019946], [cite:PUB00053744], [cite:PUB00053745], [cite:PUB00053746]]. nup2 mutants show genetic interactions with nsp1 and nup1 conditional alleles [[cite:PUB00053733], [cite:PUB00019946]]. Nup1 interacts with the nuclear import factor Srp1 [[cite:PUB00053742]] and with the small GTPase Ran (encoded by GSP1) [[cite:PUB00053743]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005643
Cellular component Nuclear pore Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
Subterm of
Part of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj0g3v0246169.1
– PREDICTED: brefeldin A resistance protein-like [Glycine max] gi|356556006|ref|XP_003546318.1|
Domains
13
Lj3g3v0139590.1
– PREDICTED: brefeldin A resistance protein-like [Glycine max] gi|356556006|ref|XP_003546318.1|
Domains
11
LotjaGi3g1v0015500.1
– Ran-binding protein 1 domain-containing; TAIR: AT1G52380.1 NUP50 (Nucleoporin 50 kDa) protein; Swiss-Prot: sp|Q9C829|NU50A_ARATH Nuclear pore complex protein NUP50A; TrEMBL-Plants: tr|A0A0B2NU93|A0A0B2NU93_GLYSO E3 SUMO-protein ligase RanBP2; Found in the gene: LotjaGi3g1v0015500
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 33.33