Description

IPR016087 is a Chalcone isomerase.

<p>Chalcone isomerase (CHI, [ec:5.5.1.6]; also known as chalcone-flavanone isomerase) is a plant enzyme responsible for the isomerisation of chalcone to naringenin, a key step in the biosynthesis of flavonoids. The Petunia hybrida (Petunia) genome contains two genes coding for very similar enzymes, ChiA and ChiB, but only the first seems to encode a functional chalcone isomerase. Chalcone isomerase has a core 2-layer α/β structure consisting of β(3)-α(2)-β-α(2)-β(3) [[cite:PUB00024704]].</p> <p>Altered inheritance of mitochondria protein 18/46, mitochondrial (AIM18/16) are CHI-like proteins from Saccharomyces cerevisiae, which lacks other enzymes of the flavonoid pathway. They show a similar fold to CHI with an extra fungal-specific loop. Instead of the chalcone isomerase activity these proteins bind heme, and structural prediction suggest this domain might be related to bacterial cytochrome P460 [[cite:PUB00103775]].</p> <p>This entry represents the chalcone isomerases domain found in proteins from plants, fungi and bacteria.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 22

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: