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IPR016914

Description

IPR016914 is a tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL.

<p>This entry represents tRNA (cytidine/uridine-2'-O-)-methyltransferase that methylate the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA) [[cite:PUB00060403]]. They catalyse the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. Some uncharacterised plant sequences are also included in this entry.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
AGAMOUS-like 26 isoform 1 [Theobroma cacao] gi|508704835|gb|EOX96731.1| 10
TRNA (cytidine(34)-2'-O)-methyltransferase; TAIR: AT5G26880.1 tRNA (cytidine(34)-2'-O)-methyltransferase; Swiss-Prot: sp|P74516|TRML_SYNY3 Putative tRNA (cytidine(34)-2'-O)-methyltransferase; TrEMBL-Plants: tr|I3S4V5|I3S4V5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0261900 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd18094 CDD 1 50.00