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IPR017665

Source: InterPro

Description

IPR017665 is a Guanylate kinase.

<p>Guanylate kinase, also called GMP kinase, is essential for recycling GMP and indirectly, cGMP. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP [[cite:PUB00022121]]. Guanylate kinase is a highly conserved monomer and is important for the activation of various antiviral drugs.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004385
Molecular function Guanylate kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP.
Subterm of
GO:0006163
Biological process Purine nucleotide metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Subterm of

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj5g3v0890630.1
– PREDICTED: guanylate kinase-like [Glycine max] gi|356504801|ref|XP_003521183.1|
Domains
20
Lj6g3v1887740.1
– PREDICTED: guanylate kinase-like isoform X1 [Cicer arietinum] gi|502078966|ref|XP_004486110.1|
Domains
16
LotjaGi0g1v0000200.1
– Guanylate kinase; TAIR: AT3G57550.1 guanylate kinase; Swiss-Prot: sp|Q9M682|GMK2_ARATH Guanylate kinase 2; TrEMBL-Plants: tr|A0A0B2P9S7|A0A0B2P9S7_GLYSO Guanylate kinase; Found in the gene: LotjaGi0g1v0000200
Domains
20
LotjaGi0g1v0000200.2
– Guanylate kinase; TAIR: AT3G57550.1 guanylate kinase; Swiss-Prot: sp|Q9M682|GMK2_ARATH Guanylate kinase 2; TrEMBL-Plants: tr|A0A0B2P9S7|A0A0B2P9S7_GLYSO Guanylate kinase; Found in the gene: LotjaGi0g1v0000200
Domains
20
LotjaGi1g1v0720600.1
– Guanylate kinase-like protein; TAIR: AT3G57550.1 guanylate kinase; Swiss-Prot: sp|Q9M682|GMK2_ARATH Guanylate kinase 2; TrEMBL-Plants: tr|A2Q3K9|A2Q3K9_MEDTR Guanylate kinase-like protein; Found in the gene: LotjaGi1g1v0720600
Domains
18
LotjaGi1g1v0720600.2
– Guanylate kinase-like protein; TAIR: AT3G57550.1 guanylate kinase; Swiss-Prot: sp|Q9M682|GMK2_ARATH Guanylate kinase 2; TrEMBL-Plants: tr|A2Q3K9|A2Q3K9_MEDTR Guanylate kinase-like protein; Found in the gene: LotjaGi1g1v0720600
Domains
18
LotjaGi6g1v0300300.1
– Guanylate kinase; TAIR: AT3G06200.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q10M74|GMK2_ORYSJ Guanylate kinase 2, chloroplastic/mitochondrial; TrEMBL-Plants: tr|A0A0L9VEL3|A0A0L9VEL3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0300300
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00071 CDD 1 14.29