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IPR018244 is a Allergen V5/Tpx-1-related, conserved site.
<p>The cysteine-rich secretory proteins (Crisp) are predominantly found in the mammalian male reproductive tract as well as in the venom of reptiles. This family includes mammalian testis-specific protein (Tpx-1), also known as cysteine-rich secretory protein 2 (CRISP2) [[cite:PUB00001948]]; venom allergen 5 from vespid wasps and venom allergen 3 from fire ants, which are potent allergens that mediate allergic reactions to stings insects of the Hymenoptera family [[cite:PUB00003182]]; scoloptoxins from Scolopendra dehaani (Thai centipede) [[cite:PUB00092777]]; plant pathogenesis proteins of the PR-1 family [[cite:PUB00001206]], which are synthesised during pathogen infection or other stress-related responses; allurin, a sperm chemoattractant [[cite:PUB00068002]], serotriflin [[cite:PUB00068003]], etc.</p> <p>The precise function of some of these proteins is still unclear. Tpx-1 or CRISP2 may regulate some ion channels' activity and thereby regulate calcium fluxes during sperm capacitation [[cite:PUB00033277]].</p> <p>This entry also includes allergen Tab y 5.0101 from horsefly salivary glands [[cite:PUB00093389]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: pathogenesis-related protein PR-1-like [Glycine max] gi|356564862|ref|XP_003550666.1| | 23 | ||
| – | Pathogenesis-related protein 1a [Medicago truncatula] gi|357446161|ref|XP_003593358.1| | 21 | ||
| – | Pathogenesis-related protein [Medicago truncatula] gi|357446157|ref|XP_003593356.1| | 21 | ||
| – | Pathogenesis-related protein 1; TAIR: AT4G25780.1 CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein; Swiss-Prot: sp|Q40374|PR1_MEDTR Pathogenesis-related protein PR-1; TrEMBL-Plants: tr|I3SHL8|I3SHL8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0297700 | 23 | ||
| – | Pathogenesis-related protein 1; TAIR: AT4G30320.1 CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein; Swiss-Prot: sp|Q40374|PR1_MEDTR Pathogenesis-related protein PR-1; TrEMBL-Plants: tr|I3SXI8|I3SXI8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0297800 | 23 | ||
| – | Pathogenesis-related protein 1; TAIR: AT4G30320.1 CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein; Swiss-Prot: sp|Q40374|PR1_MEDTR Pathogenesis-related protein PR-1; TrEMBL-Plants: tr|I3SXI8|I3SXI8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0297800 | 23 | ||
| – | Pathogenesis-related protein 1; TAIR: AT3G09590.1 CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein; Swiss-Prot: sp|Q41359|PR1_SAMNI Pathogenesis-related protein PR-1 type; TrEMBL-Plants: tr|A0A072VJU7|A0A072VJU7_MEDTR CAP, cysteine-rich secretory protein, antigen 5; Found in the gene: LotjaGi5g1v0071700 | 22 | ||
| – | Pathogenesis-related protein 1-like; TAIR: AT4G33720.1 CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein; Swiss-Prot: sp|Q9ZNS4|PRB1_ARATH Pathogenesis-related protein 1; TrEMBL-Plants: tr|I3S886|I3S886_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0345200 | 22 | ||
| – | Pathogenesis-related protein 1; TAIR: AT4G33720.1 CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein; Swiss-Prot: sp|P11670|PRB1_TOBAC Basic form of pathogenesis-related protein 1; TrEMBL-Plants: tr|I3T2D3|I3T2D3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0345300 | 22 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd05381 | CDD | 1 | 11.11 |