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IPR018983

Source: InterPro

Description

IPR018983 is a U3 small nucleolar RNA-associated protein 15, C-terminal.

<p>This entry represents the C-terminal domain of the U3 small nucleolar RNA-associated protein 15 (UTP15). This protein is involved in nucleolar processing of pre-18S ribosomal RNA, and is required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). UTP15 is a component of the ribosomal small subunit (SSU) processome, which is a large ribonucleoprotein (RNP) required for processing of precursors to the small subunit RNA, the 18S, of the ribosome [[cite:PUB00035836], [cite:PUB00035837]]. This domain is found C-terminal to the WD40 repeat ([interpro:IPR001680]). UTP15 associates with U3 snoRNA, which is ubiquitous in eukaryotes and is required for nucleolar processing of pre-18S ribosomal RNA [[cite:PUB00008496]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005730
Cellular component Nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
Subterm of
Part of
GO:0006364
Biological process RRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
Subterm of
Part of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj5g3v1681420.1
– PREDICTED: U3 small nucleolar RNA-associated protein 15 homolog [Cicer arietinum] gi|502117906|ref|XP_004496004.1|
Domains
14
LotjaGi5g1v0261100.1
– Transducin/WD-like repeat-protein; TAIR: AT2G47990.1 transducin family protein / WD-40 repeat family protein; Swiss-Prot: sp|O82266|SWA1_ARATH Protein SLOW WALKER 1; TrEMBL-Plants: tr|A0A151TWT8|A0A151TWT8_CAJCA U3 small nucleolar RNA-associated protein 15 isogeny; Found in the gene: LotjaGi5g1v0261100
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00