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IPR020602 is a GTP cyclohydrolase I domain.
<p>GTP cyclohydrolase I ([ec:3.5.4.16]) catalyses the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP [[cite:PUB00022220]]. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects. The comparison of the sequence of the enzyme from bacterial and eukaryotic sources shows that the structure of this enzyme has been extremely well conserved throughout evolution [[cite:PUB00000247]].</p> <p>This entry represents a common fold found in GTP cyclohydrolase I [[cite:PUB00035933]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | GTP cyclohydrolase I [Medicago truncatula] gi|357505161|ref|XP_003622869.1| | 8 | ||
– | GTP cyclohydrolase I [Medicago truncatula] gi|357505161|ref|XP_003622869.1| | 8 | ||
– | GTP cyclohydrolase I [Medicago truncatula] gi|357505161|ref|XP_003622869.1| | 8 | ||
– | GTP cyclohydrolase 1; TAIR: AT3G07270.1 GTP cyclohydrolase I; Swiss-Prot: sp|Q8VYU3|GCH1_SOLLC GTP cyclohydrolase 1; TrEMBL-Plants: tr|K7MSK2|K7MSK2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0591900_LC | 10 | ||
– | GTP cyclohydrolase 1; TAIR: AT3G07270.1 GTP cyclohydrolase I; Swiss-Prot: sp|Q8VYU3|GCH1_SOLLC GTP cyclohydrolase 1; TrEMBL-Plants: tr|I3T069|I3T069_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0591900_LC | 8 | ||
– | GTP cyclohydrolase 1; TAIR: AT3G07270.1 GTP cyclohydrolase I; Swiss-Prot: sp|Q8VYU3|GCH1_SOLLC GTP cyclohydrolase 1; TrEMBL-Plants: tr|K7MSK2|K7MSK2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0591900_LC | 10 | ||
– | GTP cyclohydrolase 1; TAIR: AT3G07270.1 GTP cyclohydrolase I; Swiss-Prot: sp|Q8VYU3|GCH1_SOLLC GTP cyclohydrolase 1; TrEMBL-Plants: tr|I3T069|I3T069_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0591900_LC | 8 | ||
– | GTP cyclohydrolase 1; TAIR: AT3G07270.1 GTP cyclohydrolase I; Swiss-Prot: sp|Q8VYU3|GCH1_SOLLC GTP cyclohydrolase 1; TrEMBL-Plants: tr|A0A072TL11|A0A072TL11_MEDTR GTP cyclohydrolase I 1; Found in the gene: LotjaGi3g1v0087600 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
SSF55620 | SUPERFAMILY | 1 | 12.50 |