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IPR023165

Source: InterPro

Description

IPR023165 is a rRNA adenine dimethylase-like, C-terminal.

<p>KsgA is a universally conserved rRNA adenine dimethyltransferase that catalyses the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases in 16S rRNA. This enzyme and the resulting modified adenosine bases appear to be conserved in all species of eubacteria, eukaryotes, and archaebacteria, and in eukaryotic organelles. The KsgA enzymes are homologous to another family of RNA methyltransferases, the Erm enzymes, which methylate a single adenosine base in 23S rRNA [[cite:PUB00014820]].</p> <p>This superfamily represents a rRNA adenine dimethylase-like domain present in these enzymes, which consists of four α-helices and one 3(10)-helix and forms a cleft with the N-terminal domain and is thought to stabilise it. Other studies have suggested that due to the positively charged surface patch, the C-terminal domain may be involved in recognition and binding of the ribosomal rRNA substrate, and mediates substrate specificity [[cite:PUB00052052], [cite:PUB00072555]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v2624830.1
– PREDICTED: ribosomal RNA small subunit methyltransferase A-like [Glycine max] gi|356568329|ref|XP_003552364.1|
Domains
16
LotjaGi1g1v0469600.1
– Ribosomal RNA small subunit methyltransferase A; TAIR: AT1G01860.1 Ribosomal RNA adenine dimethylase family protein; Swiss-Prot: sp|O65090|DIM1C_ARATH Ribosomal RNA small subunit methyltransferase, chloroplastic; TrEMBL-Plants: tr|I1N3K9|I1N3K9_SOYBN rRNA adenine N(6)-methyltransferase; Found in the gene: LotjaGi1g1v0469600
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00755 TIGRFAM 1 50.00