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IPR026849 is a Autophagy-related protein 2.
<p>Pexophagy is an autophagic process consisting of the rapid and selective degradation of peroxisomes. Autophagy-related protein 2 (ATG2) is required for glucose-induced micropexophagy and ethanol-induced macropexophagy in yeast [[cite:PUB00061942], [cite:PUB00061943]]. Homologues of this protein have also been described in mammals and plants. Mammalian ATG2 proteins are thought to function both in autophagosome (a structure that enclose the cytoplasmic materials) formation and regulation of lipid droplet morphology and dispersion [[cite:PUB00061944]]. In plants they have a role in programmed cell death, senescence and disease resistance [[cite:PUB00061945]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Autophagy | The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Autophagy-related protein 2 [Arabidopsis thaliana] gi|316995369|gb|ADU79134.1| | 5 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 11 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 8 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 7 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 4 | ||
| – | Autophagy-related protein 2; TAIR: AT3G19190.2 autophagy 2; Swiss-Prot: sp|F8S296|ATG2_ARATH Autophagy-related protein 2; TrEMBL-Plants: tr|G7JLA6|G7JLA6_MEDTR Autophagy protein; Found in the gene: LotjaGi4g1v0073100 | 9 | ||
| – | Autophagy-related protein 2; TAIR: AT3G19190.2 autophagy 2; Swiss-Prot: sp|F8S296|ATG2_ARATH Autophagy-related protein 2; TrEMBL-Plants: tr|G7JLA6|G7JLA6_MEDTR Autophagy protein; Found in the gene: LotjaGi4g1v0073100 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 14.29 |