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IPR026885 is a Autophagy-related protein 2, middle RBG module.
<p>The Atg2 protein, an integral membrane protein, is required for a range of functions including the regulation of autophagy in conjunction with the Atg1-Atg13 complex [[cite:PUB00035359], [cite:PUB00052352], [cite:PUB00056202]]. It is a lipid transfer protein required for autophagosome completion and peroxisome degradation. It is a member of the RBG (repeating β-grooves) superfamily, together with VPS13, SHIP164, Csf1, and the Hob proteins, which all share the same structure consisting of long hydrophobic grooves made of multiple repeating modules of five β-sheets followed by a loop [[cite:PUB00101861], [cite:PUB00101862]]. This entry represents central RBG modules.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 11 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 8 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357475421|ref|XP_003607996.1| | 7 | ||
| – | Autophagy-related protein 2; TAIR: AT3G19190.2 autophagy 2; Swiss-Prot: sp|F8S296|ATG2_ARATH Autophagy-related protein 2; TrEMBL-Plants: tr|G7JLA6|G7JLA6_MEDTR Autophagy protein; Found in the gene: LotjaGi4g1v0073100 | 9 | ||
| – | Autophagy-related protein 2; TAIR: AT3G19190.2 autophagy 2; Swiss-Prot: sp|F8S296|ATG2_ARATH Autophagy-related protein 2; TrEMBL-Plants: tr|G7JLA6|G7JLA6_MEDTR Autophagy protein; Found in the gene: LotjaGi4g1v0073100 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |