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IPR027794

Source: InterPro

Description

IPR027794 is a tRNase Z endonuclease.

<p>This domain is found in the RNase Z enzymes, which are closely related structurally to the Lactamase B family members. tRNase Z (ribonuclease Z) is the endonuclease that is involved in tRNA 3'-end maturation through removal of the 3'-trailer sequences from tRNA precursors. The fission yeast Schizosaccharomyces pombe contains two candidate tRNase Zs encoded by two essential genes. The first, Trz1, is targeted to the nucleus and has an SV40 nuclear localisation signal at its N terminus, consisting of four consecutive arginine and lysine residues between residues 208 and 211 (KKRK) that is critical for the NLS function. The second, Trz2, is targeted to the mitochondria, with an N-terminal mitochondrial targeting signal within the first 38 residues [[cite:PUB00066776]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008033
Biological process TRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj3g3v0258360.1
– PREDICTED: zinc phosphodiesterase ELAC protein 2-like isoform X1 [Cicer arietinum] gi|502081097|ref|XP_004486765.1|
Domains
8
LotjaGi3g1v0019500.1
– Ribonuclease Z; TAIR: AT3G16260.1 tRNAse Z4; Swiss-Prot: sp|Q9BQ52|RNZ2_HUMAN Zinc phosphodiesterase ELAC protein 2; TrEMBL-Plants: tr|I1M5I2|I1M5I2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0019500
Domains
11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00