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IPR029525 is a INO80 complex, subunit Ies6.
<p>This entry represents INO80 complex subunit Ies6 (also known as INO80 complex subunit C, INO80C). INO80 is involved in transcriptional regulation, DNA replication and probably DNA repair [[cite:PUB00061630]]. Together with Arp5, Ies6 promotes binding of the INO80 complex to nucleosomes to help initiate the remodeling reaction [[cite:PUB00070373]]. The homologue from Arabidopsis ENN mediates a regulatory mechanism that monitors the expression of the essential multifunctional plant stress regulator EIN2 via H3K27me3 repressive histone demethylation and histone variant H2A.Z eviction, thus modulating responses to ethylene (ET), especially during embryogenesis [[cite:PUB00101091]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Chromatin remodeling | Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. | ||
| Cellular component | Ino80 complex | A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | INO80 complex subunit C [Medicago truncatula] gi|357462405|ref|XP_003601484.1| | 6 | ||
| – | INO80 complex subunit C; TAIR: AT4G38495.1 chromatin-remodeling complex subunit; Swiss-Prot: sp|Q8BHA0|IN80C_MOUSE INO80 complex subunit C; TrEMBL-Plants: tr|I3SJK2|I3SJK2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0026800 | 5 | ||
| – | INO80 complex subunit C; TAIR: AT4G38495.1 chromatin-remodeling complex subunit; Swiss-Prot: sp|Q8BHA0|IN80C_MOUSE INO80 complex subunit C; TrEMBL-Plants: tr|I3SJK2|I3SJK2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0026800 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SM00993 | SMART | 1 | 33.33 |