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IPR030183

Description

IPR030183 is a S-type anion channel.

<p>This entry represents a family of S-type (slow current) anion channels that in Arabidopsis consists of SLAC1 (SLOW ANION CHANNEL-ASSOCIATED 1, At1g12480) and SLAC1-homologue proteins 1-4 (SLAH1-4). They have in common their plasma membrane localisation, but show distinct tissue-specific expression patterns. They are distant homologues of bacterial and fungal C4-dicarboxylate transporters [[cite:PUB00071875]].</p> <p>SLAC1 is localised specifically to the plasma membrane of guard cells [[cite:PUB00071875]]. It mediates CO2 sensitivity and is essential for stomatal closure in response to various endogenous and environmental stimuli [[cite:PUB00071874], [cite:PUB00097263], [cite:PUB00097264]], such as abscisic acid, ozone, light/dark transitions, humidity change, calcium ions, hydrogen peroxide and nitric oxide [[cite:PUB00066754]]. It also functions as an essential negative regulator of inward potassium channels in guard cells.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Cellular ion homeostasis Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
Molecular function Voltage-gated anion channel activity Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Cellular component Integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Associated Lotus transcripts 12

Transcript Name Description Predicted domains Domain count
PREDICTED: S-type anion channel SLAH3-like [Glycine max] gi|356529097|ref|XP_003533133.1| 7
PREDICTED: S-type anion channel SLAH3-like [Glycine max] gi|356561468|ref|XP_003549003.1| 10
C4-dicarboxylate transporter/malic acid transport protein [Medicago truncatula] gi|357497905|ref|XP_003619241.1| 9
S-type anion channel; TAIR: AT5G24030.1 SLAC1 homologue 3; Swiss-Prot: sp|Q9FLV9|SLAH3_ARATH S-type anion channel SLAH3; TrEMBL-Plants: tr|I1MPD1|I1MPD1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0137900 13
S-type anion channel; TAIR: AT5G24030.1 SLAC1 homologue 3; Swiss-Prot: sp|Q9FLV9|SLAH3_ARATH S-type anion channel SLAH3; TrEMBL-Plants: tr|I1MPD1|I1MPD1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0137900 13
S-type anion channel; TAIR: AT1G62280.1 SLAC1 homologue 1; Swiss-Prot: sp|Q5E930|SLAH1_ARATH S-type anion channel SLAH1; TrEMBL-Plants: tr|A0A1J7HFJ3|A0A1J7HFJ3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0468300 12
S-type anion channel; TAIR: AT1G62280.1 SLAC1 homologue 1; Swiss-Prot: sp|Q5E930|SLAH1_ARATH S-type anion channel SLAH1; TrEMBL-Plants: tr|G7JEQ3|G7JEQ3_MEDTR C4-dicarboxylate transporter/malic acid protein; Found in the gene: LotjaGi3g1v0468900_LC 15
S-type anion channel; TAIR: AT1G62280.1 SLAC1 homologue 1; Swiss-Prot: sp|Q5E930|SLAH1_ARATH S-type anion channel SLAH1; TrEMBL-Plants: tr|I3SDT0|I3SDT0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0012300 11
S-type anion channel; TAIR: AT1G62280.1 SLAC1 homologue 1; Swiss-Prot: sp|Q5E930|SLAH1_ARATH S-type anion channel SLAH1; TrEMBL-Plants: tr|I3SDT0|I3SDT0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0012300 11
S-type anion channel; TAIR: AT1G62280.1 SLAC1 homologue 1; Swiss-Prot: sp|Q5E930|SLAH1_ARATH S-type anion channel SLAH1; TrEMBL-Plants: tr|I3SDT0|I3SDT0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0012300 11
S-type anion channel; TAIR: AT1G62280.1 SLAC1 homologue 1; Swiss-Prot: sp|Q5E930|SLAH1_ARATH S-type anion channel SLAH1; TrEMBL-Plants: tr|I3SDT0|I3SDT0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0012300 11
S-type anion channel; TAIR: AT1G12480.1 C4-dicarboxylate transporter/malic acid transport protein; Swiss-Prot: sp|Q9LD83|SLAC1_ARATH Guard cell S-type anion channel SLAC1; TrEMBL-Plants: tr|G7JK66|G7JK66_MEDTR C4-dicarboxylate transporter/malic acid protein; Found in the gene: LotjaGi4g1v0211700 14

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 8.33