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IPR030384

Source: InterPro

Description

IPR030384 is a SAM-dependent methyltransferase SMT-type.

<p>Sterol 24-C-methyltransferase Erg6 from fission yeast catalyses the methyl transfer from S-adenosyl-methionine (SAM) to the C-24 of zymosterol to form fecosterol. It is involved in the biosynthesis of ergosterol, which is important for plasma membrane structure and function [[cite:PUB00072543]]. Arabidopsis contains three sterol methyltransferases (SMT1, SMT2, and SMT3) homologous to yeast Erg6 [[cite:PUB00058152]].</p> <p>This entry represents a domain found in the Erg6/SMT (S-adenosyl-L-methionine (SAM):C-24 sterol methyl transferase) proteins.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008168
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
Subterm of

Associated Lotus transcripts 11

Transcript Name Description Predicted domains Domain count
Lj0g3v0067279.1
– PREDICTED: cycloartenol-C-24-methyltransferase-like [Glycine max] gi|356544297|ref|XP_003540590.1|
Domains
8
Lj1g3v2254700.1
– PREDICTED: 24-methylenesterol C-methyltransferase 2-like [Glycine max] gi|356517628|ref|XP_003527489.1|
Domains
17
Lj1g3v2254710.1
– PREDICTED: 24-methylenesterol C-methyltransferase 2-like [Glycine max] gi|356517628|ref|XP_003527489.1|
Domains
15
Lj1g3v2254710.2
– PREDICTED: 24-methylenesterol C-methyltransferase 2-like [Glycine max] gi|356517628|ref|XP_003527489.1|
Domains
15
Lj1g3v2254710.3
– PREDICTED: 24-methylenesterol C-methyltransferase 2-like [Glycine max] gi|356517628|ref|XP_003527489.1|
Domains
15
Lj3g3v0825030.1
– S-adenosyl-L-methionine:delta24-sterol-C-methyltransferase [Glycine max] gi|351725990|ref|NP_001238391.1|
Domains
12
Lj3g3v0825030.2
– S-adenosyl-L-methionine:delta24-sterol-C-methyltransferase [Glycine max] gi|351725990|ref|NP_001238391.1|
Domains
12
LotjaGi1g1v0432300.1
– Methyltransferase; TAIR: AT1G20330.1 sterol methyltransferase 2; Swiss-Prot: sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2; TrEMBL-Plants: tr|I1K7G0|I1K7G0_SOYBN Methyltransferase; Found in the gene: LotjaGi1g1v0432300
Domains
16
LotjaGi3g1v0120400.1
– Methyltransferase; TAIR: AT5G13710.1 sterol methyltransferase 1; Swiss-Prot: sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase; TrEMBL-Plants: tr|Q43445|Q43445_SOYBN Methyltransferase; Found in the gene: LotjaGi3g1v0120400
Domains
12
LotjaGi3g1v0120400.2
– Methyltransferase; TAIR: AT5G13710.1 sterol methyltransferase 1; Swiss-Prot: sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase; TrEMBL-Plants: tr|Q43445|Q43445_SOYBN Methyltransferase; Found in the gene: LotjaGi3g1v0120400
Domains
12
LotjaGi3g1v0548800.1
– Methyltransferase; TAIR: AT5G13710.1 sterol methyltransferase 1; Swiss-Prot: sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase; TrEMBL-Plants: tr|V4VHY5|V4VHY5_9ROSI Methyltransferase; Found in the gene: LotjaGi3g1v0548800
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd02440 CDD 1 9.09