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IPR030659 is a SecY conserved site.
<p>The eubacterial secY protein [[cite:PUB00003823]] plays an important role in protein export. It interacts with the signal sequences of secretory proteins as well as with two other components of the protein translocation system: secA and secE. SecY is an integral plasma membrane protein of 419 to 492 amino acid residues that apparently contains ten transmembrane segments. Such a structure probably confers to secY a 'translocator' function, providing a channel for periplasmic and outer-membrane precursor proteins.</p> <p>Homologues of secY are found in archaebacteria [[cite:PUB00000694]]. SecY is also encoded in the chloroplast genome of some algae [[cite:PUB00001631]] where it could be involved in a prokaryotic-like protein export system across the two membranes of the chloroplast endoplasmic reticulum (CER) which is present in chromophyte and cryptophyte algae.</p> <p>In eukaryotes, the evolutionary related protein sec61-alpha plays a role in protein translocation through the endoplasmic reticulum; it is part of a trimeric complex that also consist of sec61-beta and gamma [[cite:PUB00004170]].</p> <p>This entry represents two conserved sites for secY. The first corresponds to the second transmembrane region, which is the most conserved section of these proteins. The second spans the C-terminal part of the fourth transmembrane region, a short intracellular loop, and the N-terminal part of the fifth transmembrane region.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: protein transport protein Sec61 subunit alpha-like [Glycine max] gi|356543211|ref|XP_003540056.1| | 16 | ||
| – | PREDICTED: preprotein translocase subunit secY, chloroplastic-like [Glycine max] gi|356517020|ref|XP_003527188.1| | 15 | ||
| – | PREDICTED: preprotein translocase subunit secY, chloroplastic-like [Glycine max] gi|356517020|ref|XP_003527188.1| | 18 | ||
| – | Protein transport protein Sec61 subunit alpha; TAIR: AT2G34250.1 SecY protein transport family protein; Swiss-Prot: sp|Q54XK2|SC61A_DICDI Protein transport protein Sec61 subunit alpha; TrEMBL-Plants: tr|A0A1J7HEZ2|A0A1J7HEZ2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0113300 | 17 | ||
| – | Protein transport protein Sec61 subunit alpha; TAIR: AT2G34250.1 SecY protein transport family protein; Swiss-Prot: sp|Q54XK2|SC61A_DICDI Protein transport protein Sec61 subunit alpha; TrEMBL-Plants: tr|A0A1J7HEZ2|A0A1J7HEZ2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0113300 | 17 | ||
| – | Protein translocase secy subunit, putative; TAIR: AT2G18710.1 SECY homolog 1; Swiss-Prot: sp|Q9XQU4|SECY_PEA Preprotein translocase subunit SECY, chloroplastic; TrEMBL-Plants: tr|I1KDG6|I1KDG6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0198400 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 16.67 |