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IPR030668

Source: InterPro

Description

IPR030668 is a Spermidine/spermine synthase, eukaryotes.

<p>The ubiquitous polyamines spermidine and spermine are involved in numerous cellular functions and they are essential for cell growth and proliferation. Spermidine synthase ([ec:2.5.1.16]) (putrescine aminopropyltransferase) catalyses the last step in the biosynthesis of spermidine from arginine and methionine; the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor [[cite:PUB00048416]]. Spermine synthase ([ec:2.5.1.22]) (spermidine aminopropyltransferase) converts spermidine into spermine using decarboxylated S-adenosylmethionine as the cofactor [[cite:PUB00073569]].</p> <p>This entry consists of spermidine and spermine synthases from eukaryotes.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006595
Biological process Polyamine metabolic process The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
Subterm of

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj2g3v1391590.1
– Spermidine synthase [Lotus japonicus] gi|126153731|emb|CAM35497.1|
Domains
18
LotjaGi1g1v0282100.2
– Spermidine synthase; TAIR: AT5G53120.1 spermidine synthase 3; Swiss-Prot: sp|Q94BN2|SPSY_ARATH Spermine synthase; TrEMBL-Plants: tr|A2VC29|A2VC29_LOTJA Spermine synthase; Found in the gene: LotjaGi1g1v0282100
Domains
20
LotjaGi2g1v0319700.1
– Spermidine synthase; TAIR: AT1G23820.1 spermidine synthase; Swiss-Prot: sp|Q9ZTR1|SPD1_PEA Spermidine synthase 1; TrEMBL-Plants: tr|A2VC28|A2VC28_LOTJA Spermidine synthase; Found in the gene: LotjaGi2g1v0319700
Domains
21
LotjaGi4g1v0164700.1
– Spermidine synthase; TAIR: AT1G23820.1 spermidine synthase; Swiss-Prot: sp|Q9ZTR0|SPD2_PEA Spermidine synthase 2; TrEMBL-Plants: tr|A0A151SJ65|A0A151SJ65_CAJCA Spermidine synthase 2; Found in the gene: LotjaGi4g1v0164700
Domains
21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 25.00