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IPR033961 is a Exocyst complex component Exo84.
<p>The exocyst is a highly conserved complex composed of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84, which was originally identified in Saccharomyces cerevisiae [[cite:PUB00007377]]. Mammalian homologues of all eight exocyst proteins have been identified [[cite:PUB00081886]]. The exocyst is required for exocytosis; it mediates tethering of the secretory vesicle before docking and fusion with the plasma membrane [[cite:PUB00081889]].</p> <p>Exo84 is also involved in pre-mRNA splicing [[cite:PUB00081892]] and is required for epithelial polarity in Drosophila [[cite:PUB00081893], [cite:PUB00081894]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Exocyst | A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. | ||
| Biological process | Exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: LOW QUALITY PROTEIN: exocyst complex component 8-like [Glycine max] gi|356497826|ref|XP_003517758.1| | 13 | ||
| – | PREDICTED: exocyst complex component 8-like [Cicer arietinum] gi|502175259|ref|XP_004515698.1| | 3 | ||
| – | PREDICTED: exocyst complex component 8 [Vitis vinifera] gi|225443280|ref|XP_002273667.1| | 9 | ||
| – | Uncharacterized protein isoform 1 [Theobroma cacao] gi|508780274|gb|EOY27530.1| | 9 | ||
| – | Uncharacterized protein TCM_003954 [Theobroma cacao] gi|508702467|gb|EOX94363.1| | 8 | ||
| – | Exocyst complex component 8; TAIR: AT1G10385.1 Vps51/Vps67 family (components of vesicular transport) protein; Swiss-Prot: sp|F4I4B6|EX84A_ARATH Exocyst complex component EXO84A; TrEMBL-Plants: tr|A0A1J7FYA8|A0A1J7FYA8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0572000 | 9 | ||
| – | Exocyst complex component 8; TAIR: AT1G10385.1 Vps51/Vps67 family (components of vesicular transport) protein; Swiss-Prot: sp|F4I4B6|EX84A_ARATH Exocyst complex component EXO84A; TrEMBL-Plants: tr|A0A1J7FYA8|A0A1J7FYA8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0310900 | 9 | ||
| – | Exocyst complex component 8; TAIR: AT5G49830.1 exocyst complex component 84B; Swiss-Prot: sp|Q9LTB0|EX84B_ARATH Exocyst complex component EXO84B; TrEMBL-Plants: tr|V7BCG0|V7BCG0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0343400 | 9 | ||
| – | Exocyst complex component 8; TAIR: AT5G49830.3 exocyst complex component 84B; Swiss-Prot: sp|Q9LTB0|EX84B_ARATH Exocyst complex component EXO84B; TrEMBL-Plants: tr|V7BCG0|V7BCG0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0343400 | 9 | ||
| – | Exocyst complex component 8; TAIR: AT1G10180.1 LOW protein: exocyst complex component-like protein; Swiss-Prot: sp|Q9SY60|EX84C_ARATH Exocyst complex component EXO84C; TrEMBL-Plants: tr|V7CHW6|V7CHW6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0084900 | 9 | ||
| – | Exocyst complex component 8; TAIR: AT1G10180.1 LOW protein: exocyst complex component-like protein; Swiss-Prot: sp|Q9SY60|EX84C_ARATH Exocyst complex component EXO84C; TrEMBL-Plants: tr|V7CHW6|V7CHW6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0084900 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 9.09 |