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IPR034347 is a Glutathione S-transferases Phi, C-terminal.
<p>This entry represents the C-terminal α helical domain found in the Phi subfamily (also known as GSTF) of the glutathione S-transferase (GST) family. GSTF had long been regarded as plant specific but has also been found in basidiomycete fungi [[cite:PUB00083301]].</p> <p>GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal α helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain [[cite:PUB00081906]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Glutathione S-transferase; TAIR: AT2G30860.1 glutathione S-transferase PHI 9; Swiss-Prot: sp|O80852|GSTF9_ARATH Glutathione S-transferase F9; TrEMBL-Plants: tr|I3SZ71|I3SZ71_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0045500 | 21 | ||
– | Glutathione S-transferase; TAIR: AT2G47730.1 glutathione S-transferase phi 8; Swiss-Prot: sp|Q96266|GSTF8_ARATH Glutathione S-transferase F8, chloroplastic; TrEMBL-Plants: tr|B7FIJ1|B7FIJ1_MEDTR Uncharacterized protein; Found in the gene: LotjaGi5g1v0002600 | 20 | ||
– | Glutathione S-transferase; TAIR: AT2G47730.1 glutathione S-transferase phi 8; Swiss-Prot: sp|P30109|GSTF1_TOBAC Glutathione S-transferase PARB; TrEMBL-Plants: tr|I3S451|I3S451_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0252100 | 21 | ||
– | Glutathione S-transferase; TAIR: AT3G62760.1 Glutathione S-transferase family protein; Swiss-Prot: sp|Q9LZI9|GSTFD_ARATH Glutathione S-transferase F13; TrEMBL-Plants: tr|I1JFH4|I1JFH4_SOYBN Phi class glutathione S-transferase; Found in the gene: LotjaGi5g1v0252200 | 20 | ||
– | Glutathione S-transferase; TAIR: AT3G03190.1 glutathione S-transferase F11; Swiss-Prot: sp|Q96324|GSTFB_ARATH Glutathione S-transferase F11; TrEMBL-Plants: tr|A0A151U9M6|A0A151U9M6_CAJCA Glutathione S-transferase; Found in the gene: LotjaGi6g1v0052500 | 21 | ||
– | Glutathione S-transferase; TAIR: AT2G30860.1 glutathione S-transferase PHI 9; Swiss-Prot: sp|O80852|GSTF9_ARATH Glutathione S-transferase F9; TrEMBL-Plants: tr|I3SB85|I3SB85_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0176100 | 21 | ||
– | Glutathione S-transferase; TAIR: AT2G30860.1 glutathione S-transferase PHI 9; Swiss-Prot: sp|O80852|GSTF9_ARATH Glutathione S-transferase F9; TrEMBL-Plants: tr|A0A0L9V9U9|A0A0L9V9U9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0176200 | 19 | ||
– | Glutathione S-transferase; TAIR: AT2G30860.1 glutathione S-transferase PHI 9; Swiss-Prot: sp|O80852|GSTF9_ARATH Glutathione S-transferase F9; TrEMBL-Plants: tr|I3T6E5|I3T6E5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0176200 | 21 | ||
– | Glutathione S-transferase; TAIR: AT2G30860.1 glutathione S-transferase PHI 9; Swiss-Prot: sp|O80852|GSTF9_ARATH Glutathione S-transferase F9; TrEMBL-Plants: tr|I3T6E5|I3T6E5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0176600 | 21 | ||
– | Glutathione S-transferase; TAIR: AT2G30860.1 glutathione S-transferase PHI 9; Swiss-Prot: sp|O80852|GSTF9_ARATH Glutathione S-transferase F9; TrEMBL-Plants: tr|V7BJR0|V7BJR0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0176700 | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd03187 | CDD | 1 | 10.00 |