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IPR035907

Source: InterPro

Description

IPR035907 is a 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily.

<p>7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase ([ec:2.7.6.3]) (HPPK) catalyses the attachment of pyrophosphate to 6-hydroxymethyl-7,8-dihydropterin to form 6-hydroxymethyl-7,8-dihydropteridine pyrophosphate. This is the first step in a three-step pathway leading to 7,8 dihydrofolate. Bacterial HPPK (gene folK or sulD) [[cite:PUB00002198]] is a protein of 160 to 270 amino acids. In the lower eukaryote Pneumocystis carinii, HPPK is the central domain of a multifunctional folate synthesis enzyme (gene fas) [[cite:PUB00001816]].</p> <p>The structure of HPPK consists of an α/β sandwich with antiparallel β sheets.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
LotjaGi2g1v0292900.1
– Dihydropteroate synthase, putative; TAIR: AT4G30000.1 Dihydropterin pyrophosphokinase / Dihydropteroate synthase; Swiss-Prot: sp|O04862|FOLM_PEA Folate synthesis bifunctional protein, mitochondrial; TrEMBL-Plants: tr|G7JY17|G7JY17_MEDTR Dihydropterin pyrophosphokinase/dihydropteroate synthase; Found in the gene: LotjaGi2g1v0292900
Domains
21
LotjaGi2g1v0292900.2
– Dihydropteroate synthase, putative; TAIR: AT4G30000.1 Dihydropterin pyrophosphokinase / Dihydropteroate synthase; Swiss-Prot: sp|O04862|FOLM_PEA Folate synthesis bifunctional protein, mitochondrial; TrEMBL-Plants: tr|G7JY17|G7JY17_MEDTR Dihydropterin pyrophosphokinase/dihydropteroate synthase; Found in the gene: LotjaGi2g1v0292900
Domains
21
LotjaGi2g1v0292900.3
– Dihydropteroate synthase, putative; TAIR: AT4G30000.1 Dihydropterin pyrophosphokinase / Dihydropteroate synthase; Swiss-Prot: sp|O04862|FOLM_PEA Folate synthesis bifunctional protein, mitochondrial; TrEMBL-Plants: tr|A0A1J7HKC0|A0A1J7HKC0_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0292900
Domains
21
LotjaGi2g1v0292900.4
– Dihydropteroate synthase, putative; TAIR: AT4G30000.1 Dihydropterin pyrophosphokinase / Dihydropteroate synthase; Swiss-Prot: sp|O04862|FOLM_PEA Folate synthesis bifunctional protein, mitochondrial; TrEMBL-Plants: tr|A0A1J7HKC0|A0A1J7HKC0_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0292900
Domains
21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00739 CDD 1 25.00