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IPR036075 is a Damage-control phosphatase ARMT1-like, metal-binding domain superfamily.
<p>This superfamily represents a domain found in Damage-control phosphatases ARMT1, YMR027W from S. cerevisiae ([pdbe:3PT1]) and At2g17340 from Arabidopsis thaliana, and it is also found at the C-terminal portion of eukaryotic pantothenate kinases [[cite:PUB00038288], [cite:PUB00088731]]. Despite a first characterization of ARMT1 as a carboxyl methyltransferase, a second study suggests that these proteins are hydrolases whose function is to limit potentially harmful buildups of phosphometabolites [[cite:PUB00088733]]. They are metal-dependent phosphatases involved in metabolic damage-control processes termed "damage pre-emption" or "housecleaning". Crystal structure of damage-control phosphatase At2g17340 revealed a novel protein fold and several conserved residues coordinating a metal ion (probably Mg2) with high degree of conservation suggesting that the metal-binding site is central for the function of this domain [[cite:PUB00088733]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Pantothenate kinase; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|K7KVS7|K7KVS7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0179800 | 19 | ||
| – | Pantothenate kinase; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|K7KVS7|K7KVS7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0179800 | 18 | ||
| – | Pantothenate kinase; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|K7KVS7|K7KVS7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0179800 | 18 | ||
| – | Pantothenate kinase; TAIR: AT4G35360.1 pantothenate kinase; Swiss-Prot: sp|Q949P3|Y2734_ARATH Uncharacterized protein At2g17340; TrEMBL-Plants: tr|I3T472|I3T472_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161600 | 11 | ||
| – | Pantothenate kinase; TAIR: AT4G35360.1 pantothenate kinase; Swiss-Prot: sp|Q949P3|Y2734_ARATH Uncharacterized protein At2g17340; TrEMBL-Plants: tr|I3T472|I3T472_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161600 | 11 | ||
| – | Pantothenate kinase; TAIR: AT4G35360.1 pantothenate kinase; Swiss-Prot: sp|Q949P3|Y2734_ARATH Uncharacterized protein At2g17340; TrEMBL-Plants: tr|I3T472|I3T472_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0161600 | 7 | ||
| – | Pantothenate kinase; TAIR: AT4G35360.3 pantothenate kinase; Swiss-Prot: sp|Q949P3|Y2734_ARATH Uncharacterized protein At2g17340; TrEMBL-Plants: tr|D7U4Q7|D7U4Q7_VITVI Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0204600_LC | 6 | ||
| – | Pantothenate kinase, putative; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|K7MKQ2|K7MKQ2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0234000 | 19 | ||
| – | Pantothenate kinase, putative; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|K7MKQ2|K7MKQ2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0234000 | 16 | ||
| – | Pantothenate kinase, putative; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|I1MTH1|I1MTH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0234000 | 16 | ||
| – | Pantothenate kinase, putative; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|I1MTH1|I1MTH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0234000 | 19 | ||
| – | Pantothenate kinase, putative; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|I1MTH1|I1MTH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0234000 | 16 | ||
| – | Pantothenate kinase, putative; TAIR: AT4G32180.1 pantothenate kinase 2; Swiss-Prot: sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2; TrEMBL-Plants: tr|I1MTH1|I1MTH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0234000 | 16 | ||
| – | Pantothenate kinase; TAIR: AT4G35360.1 pantothenate kinase; Swiss-Prot: sp|Q949P3|Y2734_ARATH Uncharacterized protein At2g17340; TrEMBL-Plants: tr|K7N4U8|K7N4U8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0194600 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF111321 | SUPERFAMILY | 1 | 7.14 |