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IPR036189

Source: InterPro

Description

IPR036189 is a mRNA decapping protein 2, Box A domain superfamily.

<p>This superfamily represents the box A specific to mRNA decapping protein 2 [swissprot:P53550], Dcp2, the catalytic subunit of the mRNA-decapping enzyme [[cite:PUB00010148]], which is found at the N-terminal of the NUDIX hydrolase domain [interpro:IPR000086]. Removal of the cap structure is mediated by the Dcp1-Dcp2 complex [[cite:PUB00033653]].</p> <p>The Box A domain contains a four helices fold and an orthogonal array of two α-hairpins topology.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of
GO:0016787
Molecular function Hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
Subterm of
GO:0030145
Molecular function Manganese ion binding Interacting selectively and non-covalently with manganese (Mn) ions.
Subterm of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
LotjaGi2g1v0119900.1
– MRNA decapping protein 2; TAIR: AT5G13570.1 decapping 2; Swiss-Prot: sp|Q8GW31|DCP2_ARATH mRNA-decapping enzyme subunit 2; TrEMBL-Plants: tr|A0A0L9TCG1|A0A0L9TCG1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0119900
Domains
17
LotjaGi2g1v0119900.3
– MRNA decapping protein 2; TAIR: AT5G13570.1 decapping 2; Swiss-Prot: sp|Q8GW31|DCP2_ARATH mRNA-decapping enzyme subunit 2; TrEMBL-Plants: tr|A0A0L9TCG1|A0A0L9TCG1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0119900
Domains
17
LotjaGi2g1v0119900.5
– MRNA decapping protein 2; TAIR: AT5G13570.1 decapping 2; Swiss-Prot: sp|Q8GW31|DCP2_ARATH mRNA-decapping enzyme subunit 2; TrEMBL-Plants: tr|C6TF29|C6TF29_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0119900
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03672 CDD 1 33.33