Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR036189

Description

IPR036189 is a mRNA decapping protein 2, Box A domain superfamily.

<p>This superfamily represents the box A specific to mRNA decapping protein 2 [swissprot:P53550], Dcp2, the catalytic subunit of the mRNA-decapping enzyme [[cite:PUB00010148]], which is found at the N-terminal of the NUDIX hydrolase domain [interpro:IPR000086]. Removal of the cap structure is mediated by the Dcp1-Dcp2 complex [[cite:PUB00033653]].</p> <p>The Box A domain contains a four helices fold and an orthogonal array of two α-hairpins topology.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Molecular function Hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
Molecular function Manganese ion binding Interacting selectively and non-covalently with manganese (Mn) ions.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
MRNA decapping protein 2; TAIR: AT5G13570.1 decapping 2; Swiss-Prot: sp|Q8GW31|DCP2_ARATH mRNA-decapping enzyme subunit 2; TrEMBL-Plants: tr|A0A0L9TCG1|A0A0L9TCG1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0119900 17
MRNA decapping protein 2; TAIR: AT5G13570.1 decapping 2; Swiss-Prot: sp|Q8GW31|DCP2_ARATH mRNA-decapping enzyme subunit 2; TrEMBL-Plants: tr|A0A0L9TCG1|A0A0L9TCG1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0119900 17
MRNA decapping protein 2; TAIR: AT5G13570.1 decapping 2; Swiss-Prot: sp|Q8GW31|DCP2_ARATH mRNA-decapping enzyme subunit 2; TrEMBL-Plants: tr|C6TF29|C6TF29_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0119900 17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03672 CDD 1 33.33