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IPR036494 is a Ku, C-terminal domain superfamily.
<p>The non-homologous end joining (NHEJ) pathway is one method by which double stranded breaks in chromosomal DNA are repaired. Ku is a component of a multi-protein complex that is involved in the NHEJ. Ku has affinity for DNA ends and recruits the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Ku also binds RNA, mediating the assembly of DNA-PKcs which has a role in ribosomal RNA biogenesis [[cite:PUB00094626]]. This domain is found at the C-terminal of Ku which binds to DNA-PKcs [[cite:PUB00030095]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | ATP-dependent DNA helicase 2 subunit KU80; TAIR: AT1G48050.1 Ku80 family protein; Swiss-Prot: sp|Q9FQ09|KU80_ARATH ATP-dependent DNA helicase 2 subunit KU80; TrEMBL-Plants: tr|G7JDE1|G7JDE1_MEDTR ATP-dependent DNA helicase 2 subunit KU80; Found in the gene: LotjaGi3g1v0433200 | 29 | ||
| – | ATP-dependent DNA helicase 2 subunit KU80; TAIR: AT1G48050.1 Ku80 family protein; Swiss-Prot: sp|Q9FQ09|KU80_ARATH ATP-dependent DNA helicase 2 subunit KU80; TrEMBL-Plants: tr|G7JDE1|G7JDE1_MEDTR ATP-dependent DNA helicase 2 subunit KU80; Found in the gene: LotjaGi3g1v0433200 | 29 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00873 | CDD | 1 | 50.00 |