Description

IPR036874 is a Carbonic anhydrase superfamily.

<p>Carbonic anhydrases ([ec:4.2.1.1]) (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate [[cite:PUB00002753]]. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation [[cite:PUB00004782]]. CA has a resolvase-like fold, which has a core structure composed of three layers (α/β/α) arranged in mixed β-sheet of five strands where strand 5 is antiparallel to the rest. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a superfamily distinct from the one which groups the many different forms of eukaryotic CA's (see [interpro:IPR036398]).</p> <p>This superfamily also includes the Bacillus subtilis protein YbcF that does not seem to be able to bind zinc, which all carbonic anhydrases are thought to require, and a carbon disulfide hydrolase from acidothermophilic archaeon Acidianus, which has a typical carbonic anhydrase fold and active site but does not use CO(2) as a substrate [[cite:PUB00086422]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 8

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: