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IPR037813 is a Transcription initiation factor TFIID subunit 2.
<p>Transcription initiation factor TFIID subunit 2 (TAF2) is a component of the general purpose transcription factor complex TFIID [[cite:PUB00087656], [cite:PUB00087622]]. This entry includes TAF2 from animals, plants and fungi.</p> <p>The DNA-binding general transcription factor complex TFIID is central to the initiation of DNA-dependent RNA polymerase II transcription. TFIID is the only general transcription initiation factor that bind to the TATA box. The binding of TFIID to the TATA-box is the first step in the formation of a complex able to initiate transcription [[cite:PUB00087636]]. TFIID consists of the TATA binding protein (TBP) and 14 TBP-associated factors (TAFs). One copy of each TAF1, TAF2, TAF3, TAF7, TAF8, TAF11, TAF13, two copies of each TAF4, TAF5, TAF6, TAF9, TAF10, TAF12, and three copies of TAF14 [[cite:PUB00087622]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Transcription factor TFIID complex | A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Transcription initiation factor TFIID subunit 2; TAIR: AT1G73960.1 TBP-associated factor 2; Swiss-Prot: sp|Q8LPF0|TAF2_ARATH Transcription initiation factor TFIID subunit 2; TrEMBL-Plants: tr|A0A1J7I063|A0A1J7I063_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0263300_LC | 2 | ||
| – | Transcription initiation factor TFIID subunit 2; TAIR: AT1G73960.1 TBP-associated factor 2; Swiss-Prot: sp|Q8LPF0|TAF2_ARATH Transcription initiation factor TFIID subunit 2; TrEMBL-Plants: tr|K7KNH3|K7KNH3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0263600 | 13 | ||
| – | Transcription initiation factor TFIID subunit 2; TAIR: AT1G73960.1 TBP-associated factor 2; Swiss-Prot: sp|Q8LPF0|TAF2_ARATH Transcription initiation factor TFIID subunit 2; TrEMBL-Plants: tr|V7CAF2|V7CAF2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0263600 | 11 | ||
| – | Transcription initiation factor TFIID subunit 2; TAIR: AT1G73960.1 TBP-associated factor 2; Swiss-Prot: sp|Q8LPF0|TAF2_ARATH Transcription initiation factor TFIID subunit 2; TrEMBL-Plants: tr|K7KNH3|K7KNH3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0063100_LC | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |