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IPR038870

Description

IPR038870 is a Ubiquitin-associated protein 1.

<p>UBAP1 is a subunit of ESCRT-I, a complex facilitating endosomal sorting of ubiquitinated cargo [[cite:PUB00088507]]. It interacts with ubiquitin via a SOUBA domain [[cite:PUB00065904]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Cellular component ESCRT I complex An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.
Molecular function Ubiquitin binding Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
Biological process Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Proline-rich cell wall-like protein; TAIR: AT5G53330.1 Ubiquitin-associated/translation elongation factor EF1B protein; Swiss-Prot: sp|Q9NZ09|UBAP1_HUMAN Ubiquitin-associated protein 1; TrEMBL-Plants: tr|I3SQZ2|I3SQZ2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0277000 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00