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IPR039764

Source: InterPro

Description

IPR039764 is a RNA binding protein HABP4/SERBP1-like.

<p>This entry includes proteins with a hyaluronan/mRNA-binding protein domain, found in the HABP4 protein family of hyaluronan-binding proteins, and the PAI-1 mRNA-binding protein, PAI-RBP1 (also known as SERBP1). HABP4 has been observed to bind hyaluronan (a glucosaminoglycan), but it is not known whether this is its primary role in vivo. It has also been observed to bind RNA, but with a lower affinity than that for hyaluronan [[cite:PUB00008623]]. PAI-1 mRNA-binding protein specifically binds the mRNA of type-1 plasminogen activator inhibitor (PAI-1), and is thought to be involved in regulation of mRNA stability [[cite:PUB00008624]]. However, in both cases, the sequence motifs predicted to be important for ligand binding are not conserved throughout the family, so it is not known whether members of this family share a common function.</p> <p>Hyaluronan/mRNA-binding protein may be involved in nuclear functions such as the remodelling of chromatin and the regulation of transcription [[cite:PUB00053771], [cite:PUB00053772]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0495200.1
– RNA binding protein, putative; TAIR: AT4G17520.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23593|RGGB_ARATH RGG repeats nuclear RNA binding protein B; TrEMBL-Plants: tr|I3STC5|I3STC5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0495200
Domains
10
LotjaGi2g1v0330700_LC.1
– RNA binding protein; TAIR: AT5G47210.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|Q9LVT8|RGGC_ARATH RGG repeats nuclear RNA binding protein C; TrEMBL-Plants: tr|A0A1J7HKP6|A0A1J7HKP6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0330700_LC
Domains
6
LotjaGi2g1v0330700_LC.2
– RNA binding protein, putative; TAIR: AT4G16830.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23523|RGGA_ARATH RGG repeats nuclear RNA binding protein A; TrEMBL-Plants: tr|Q2PEQ5|Q2PEQ5_TRIPR Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0330700_LC
Domains
8
LotjaGi2g1v0330700_LC.3
– RNA binding protein; TAIR: AT5G47210.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|Q9LVT8|RGGC_ARATH RGG repeats nuclear RNA binding protein C; TrEMBL-Plants: tr|A0A1J7HKP6|A0A1J7HKP6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0330700_LC
Domains
6
LotjaGi3g1v0067700.1
– RNA binding protein, putative; TAIR: AT4G17520.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23593|RGGB_ARATH RGG repeats nuclear RNA binding protein B; TrEMBL-Plants: tr|A0A1J7GE57|A0A1J7GE57_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0067700
Domains
10
LotjaGi3g1v0403600_LC.1
– RNA binding protein, putative; TAIR: AT4G17520.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23593|RGGB_ARATH RGG repeats nuclear RNA binding protein B; TrEMBL-Plants: tr|A0A1J7H3A4|A0A1J7H3A4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0403600_LC
Domains
7
LotjaGi3g1v0403600_LC.2
– RNA binding protein, putative; TAIR: AT4G17520.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23593|RGGB_ARATH RGG repeats nuclear RNA binding protein B; TrEMBL-Plants: tr|Q2PEQ5|Q2PEQ5_TRIPR Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0403600_LC
Domains
7
LotjaGi3g1v0403600_LC.3
– RNA binding protein, putative; TAIR: AT4G17520.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23593|RGGB_ARATH RGG repeats nuclear RNA binding protein B; TrEMBL-Plants: tr|A0A1J7H3A4|A0A1J7H3A4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0403600_LC
Domains
7
LotjaGi3g1v0403600_LC.6
– RNA binding protein, putative; TAIR: AT4G17520.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23593|RGGB_ARATH RGG repeats nuclear RNA binding protein B; TrEMBL-Plants: tr|A0A1J7H3A4|A0A1J7H3A4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0403600_LC
Domains
11
LotjaGi5g1v0009500_LC.1
– RNA binding protein, putative; TAIR: AT4G16830.1 Hyaluronan / mRNA binding family; Swiss-Prot: sp|O23523|RGGA_ARATH RGG repeats nuclear RNA binding protein A; TrEMBL-Plants: tr|Q2PEQ5|Q2PEQ5_TRIPR Putative uncharacterized protein; Found in the gene: LotjaGi5g1v0009500_LC
Domains
7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 10.00