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IPR043162 is a Dedicator of cytokinesis, C-terminal, lobe C.
<p>DOCK (dedicator of cytokinesis) proteins are potential guanine nucleotide exchange factors that activate some small GTPases, such as Rac, by exchanging bound GDP for free GTP [[cite:PUB00014935]]. DOCK proteins are required during several cellular processes, such as cell motility and phagocytosis [[cite:PUB00014936]]. Nucleotide exchange is catalysed by a conserved catalytic DHR2 domain situated within the C-terminal region which consists of three lobes.</p> <p>This entry represents lobe C of DHR2 which folds to form an antiparallel α-helical bundle [[cite:PUB00061816]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Dedicator of cytokinesis; TAIR: AT4G16340.1 guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein; Swiss-Prot: sp|Q8SAB7|SPK1_ARATH Guanine nucleotide exchange factor SPIKE 1; TrEMBL-Plants: tr|K7MCT0|K7MCT0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0299000 | 19 | ||
– | Dedicator of cytokinesis; TAIR: AT4G16340.1 guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein; Swiss-Prot: sp|Q8SAB7|SPK1_ARATH Guanine nucleotide exchange factor SPIKE 1; TrEMBL-Plants: tr|A0A0R0IQP1|A0A0R0IQP1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0299000 | 16 | ||
– | Dedicator of cytokinesis; TAIR: AT4G16340.1 guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein; Swiss-Prot: sp|Q8SAB7|SPK1_ARATH Guanine nucleotide exchange factor SPIKE 1; TrEMBL-Plants: tr|A0A0R0G4P9|A0A0R0G4P9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0299000 | 18 | ||
– | Dedicator of cytokinesis; TAIR: AT4G16340.1 guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein; Swiss-Prot: sp|Q8SAB7|SPK1_ARATH Guanine nucleotide exchange factor SPIKE 1; TrEMBL-Plants: tr|K7MCT0|K7MCT0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0299000 | 19 | ||
– | Dedicator of cytokinesis; TAIR: AT4G16340.1 guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein; Swiss-Prot: sp|Q8SAB7|SPK1_ARATH Guanine nucleotide exchange factor SPIKE 1; TrEMBL-Plants: tr|A0A0R0G4P9|A0A0R0G4P9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0299000 | 24 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 20.00 |