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MF_00527

Description

Putative 3-methyladenine DNA glycosylase.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Molecular function Alkylbase DNA N-glycosylase activity Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
Biological process Base-excision repair In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
DNA-3-methyladenine glycosylase; TAIR: AT3G12040.1 DNA-3-methyladenine glycosylase (MAG); Swiss-Prot: sp|Q39147|3MG_ARATH DNA-3-methyladenine glycosylase; TrEMBL-Plants: tr|I1N9A6|I1N9A6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0279000 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00