Domain Predictions — View

Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

PF05450

Source: Pfam

Description

Nicastrin

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0016021 View details of GO:0016021 AmiGO InterPro QuickGO	Cellular component	Integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	Subterm of GO:0031224
GO:0016485 View details of GO:0016485 AmiGO InterPro QuickGO	Biological process	Protein processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.	Subterm of GO:0006508 GO:0051604

Associated Lotus transcripts 4

Transcript	Name	Description	Predicted domains	Domain count
Lj3g3v2989260.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: nicalin-1-like [Glycine max] gi\|356539234\|ref\|XP_003538104.1\|	Domains CYTOPLASMIC_DOMAIN Coil G3DSA:3.40.630.10 IPR008710 IPR018247 NON_CYTOPLASMIC_DOMAIN PF05450 PS00018 PTHR31826 SSF53187 TMhelix TRANSMEMBRANE cd03882	13
Lj6g3v0409420.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: nicastrin-like [Glycine max] gi\|356539812\|ref\|XP_003538387.1\|	Domains G3DSA:3.40.630.10 IPR008710 NON_CYTOPLASMIC_DOMAIN PF05450 PTHR21092 PTHR21092:SF0 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF53187 SignalP-noTM_EUK	12
LotjaGi3g1v0475000.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Nicalin; TAIR: AT3G44330.1 M28 Zn-peptidase nicastrin; Swiss-Prot: sp\|Q6NZ07\|NCLN_DANRE Nicalin-1; TrEMBL-Plants: tr\|A0A151TNY8\|A0A151TNY8_CAJCA Nicalin; Found in the gene: LotjaGi3g1v0475000	Domains CYTOPLASMIC_DOMAIN Coil G3DSA:3.40.630.10 IPR016574 IPR018247 NON_CYTOPLASMIC_DOMAIN PF05450 PIRSF011018 PS00018 PS51257 PTHR31826 PTHR31826:SF5 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF53187 TMhelix TRANSMEMBRANE cd03882	20
LotjaGi6g1v0054700.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Nicastrin; TAIR: AT3G52640.1 Zn-dependent exopeptidases superfamily protein; Swiss-Prot: sp\|Q8GUM5\|NICA_ARATH Nicastrin; TrEMBL-Plants: tr\|A0A0B2QWJ0\|A0A0B2QWJ0_GLYSO Nicastrin; Found in the gene: LotjaGi6g1v0054700	Domains CYTOPLASMIC_DOMAIN G3DSA:3.40.630.10 IPR008710 IPR041084 NON_CYTOPLASMIC_DOMAIN PF05450 PF18266 PTHR21092 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF53187 SignalP-noTM TMhelix TRANSMEMBRANE cd03881	17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
cd03881	CDD	1	25.00